Oligomeric Structure of Type I and Type II Transforming Growth Factor β Receptors: Homodimers Form in the ER and Persist at the Plasma Membrane

Antibodies, a laboratory manual

1989 • 12,929 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

Transforming growth factor beta

2011 • 1,990 citations

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights

1990 • 992 citations

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

1987 • 949 citations

Betaglycan presents ligand to the TGFβ signaling receptor

1993 • 887 citations

Receptor-associated Mad homologues synergize as effectors of the TGF-β response

1996 • 874 citations

The structure of an antigenic determinant in a protein

1984 • 841 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-β receptor system

1991 • 661 citations

Receptors for the TGF-β family

1992 • 638 citations

Expression cloning and characterization of the TGF-β type III receptor

1991 • 638 citations

The TGF-β family and its composite receptors

1994 • 539 citations

[35] Epitope tagging and protein surveillance

1991 • 526 citations

Electron tomography : three-dimensional imaging with the transmission electron microscope

1992 • 354 citations

A Transforming Growth Factor β Type I Receptor that Signals to Activate Gene Expression

1994 • 296 citations

TGF-β receptors and actions

1994 • 291 citations

Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

1991 • 252 citations

The types II and III transforming growth factor-beta receptors form homo-oligomers.

1994 • 199 citations

Serine/threonine kinase receptors: mediators of transforming growth factor beta family signals.

1996 • 197 citations

Growth inhibition by transforming growth factor beta (TGF-beta) type I is restored in TGF-beta-resistant hepatoma cells after expression of TGF-beta receptor type II cDNA.

1993 • 192 citations

The transforming growth factor beta receptors types I, II, and III form hetero-oligomeric complexes in the presence of ligand.

1993 • 181 citations

Receptors for the TGF-β superfamily: multiple polypeptides and serine/threonine kinases

1993 • 164 citations

Signal transduction by members of the transforming growth factor-β superfamily

1996 • 160 citations

Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

1996 • 158 citations

IVE (Image Visualization Environment): A Software Platform for All Three-Dimensional Microscopy Applications

1996 • 147 citations

Homomeric interactions between type II transforming growth factor-beta receptors.

1994 • 137 citations

Positive and negative regulation of type II TGF-beta receptor signal transduction by autophosphorylation on multiple serine residues

1997 • 125 citations

Signaling by chimeric erythropoietin-TGF-beta receptors: homodimerization of the cytoplasmic domain of the type I TGF-beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction.

1996 • 120 citations

The Soluble Exoplasmic Domain of the Type II Transforming Growth Factor (TGF)-β Receptor

1995 • 116 citations

Biosynthesis of the Type I and Type II TGF-β Receptors

1997 • 83 citations

Isoform-specific transforming growth factor-beta binding proteins with membrane attachments sensitive to phosphatidylinositol-specific phospholipase C.

1991 • 80 citations

Phosphorylation-dependent Interaction of the Cytoplasmic Domains of the Type I and Type II Transforming Growth Factor-β Receptors

1995 • 80 citations

TGF-beta receptors: structure and function.

1994 • 63 citations

Sendai virus envelope glycoproteins become laterally mobile on the surface of human erythrocytes following fusion

1985 • 33 citations

Preparation of F(ab′)2 fragments from monoclonal mouse IgG1 suitable for use in radioimaging

1988 • 29 citations

Characterization of transforming growth factor-beta (TGF-beta) receptors on BeWo choriocarcinoma cells including the identification of a novel 38-kDa TGF-beta binding glycoprotein.

1992 • 27 citations

Design and construction of an optimal illumination system for quantitative wide‐field multi‐dimensional microscopy

1993 • 27 citations

Ligand-Induced Dimerization of the Extracellular Domain of the TGF-β Receptor Type II

1996 • 13 citations

Analysis of Three-Dimensional Image Data: Display and Feature Tracking

1992 • 7 citations

Design and construction of an optimal illumination system for quantitative wide‐field multi‐dimensional microscopy

1993 • 7 citations