Multiple Oncogenic Pathway Signatures Show Coordinate Expression Patterns in Human Prostate Tumors

The Hallmarks of Cancer

2000 • 27,569 citations

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Statistical significance for genomewide studies

2003 • 9,411 citations

Java Treeview—extensible visualization of microarray data

2004 • 2,963 citations

Gene expression correlates of clinical prostate cancer behavior

2002 • 2,504 citations

Molecular determinants of resistance to antiandrogen therapy

2003 • 2,212 citations

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

2005 • 2,015 citations

Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors

2002 • 1,465 citations

Gene expression profiling identifies clinically relevant subtypes of prostate cancer

2004 • 1,292 citations

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

2004 • 951 citations

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

2000 • 830 citations

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

2003 • 787 citations

Gene Expression Alterations in Prostate Cancer Predicting Tumor Aggression and Preceding Development of Malignancy

2004 • 753 citations

Molecular genetics of prostate cancer

2000 • 723 citations

Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.

2002 • 656 citations

Discovering statistically significant pathways in expression profiling studies

2005 • 638 citations

Gene expression profiling predicts clinical outcome of prostate cancer

2004 • 448 citations

A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer

2003 • 421 citations

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis

2004 • 420 citations

Real-Time PCR Analysis of DNA and RNA Extracted from Formalin-Fixed and Paraffin-Embedded Biopsies

2001 • 397 citations

Activation of Mitogen-Activated Protein Kinase in Estrogen Receptor α–Positive Breast Cancer Cells In vitro Induces an In vivo Molecular Phenotype of Estrogen Receptor α–Negative Human Breast Tumors

2006 • 232 citations

Transcriptional programs activated by exposure of human prostate cancer cells to androgen

2002 • 192 citations

SRCgene expression in human cancer: the role of transcriptional activation

2004 • 159 citations

Molecular pathology of prostate cancer

2005 • 157 citations

Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivoin tumor xenografts and human breast tumors

2006 • 118 citations

Identification of an Integrated SV40 T/t-Antigen Cancer Signature in Aggressive Human Breast, Prostate, and Lung Carcinomas with Poor Prognosis

2007 • 102 citations

Expression of a Truncated Form of the c-Kit Tyrosine Kinase Receptor and Activation of Src Kinase in Human Prostatic Cancer

2004 • 83 citations