T Cell Receptor-Dependent Regulation of Lipid Rafts Controls Naive CD8+ T Cell Homeostasis

Lipid rafts and signal transduction

2000 • 6,079 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Reversible Defects in Natural Killer and Memory Cd8 T Cell Lineages in Interleukin 15–Deficient Mice

2000 • 1,578 citations

Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

1998 • 1,262 citations

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells

2006 • 770 citations

The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery

1999 • 742 citations

Peripheral Selection of the T Cell Repertoire

1991 • 666 citations

CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity

1998 • 643 citations

Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines

2003 • 582 citations

Interaction of the IL-2 Receptor with thesrc-Family Kinase p56^lck: Identification of Novel Intermolecular Association

1991 • 576 citations

Antigen-independent activation of naive and memory resting T cells by a cytokine combination.

1994 • 541 citations

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4+ T Cells

2001 • 538 citations

IL-21 Is Required to Control Chronic Viral Infection

2009 • 536 citations

A Role for CD5 in TCR-Mediated Signal Transduction and Thymocyte Selection

1995 • 437 citations

Converting IL-15 to a superagonist by binding to soluble IL-15Rα

2006 • 388 citations

DO11.10 and OT-II T Cells Recognize a C-Terminal Ovalbumin 323–339 Epitope

2000 • 334 citations

Homeostatic T Cell Proliferation

2000 • 279 citations

Cytokines and T-cell homeostasis

2007 • 278 citations

Fine Tuning of TCR Signaling by CD5

2001 • 270 citations

A Role for TCR Affinity in Regulating Naive T Cell Homeostasis

2004 • 235 citations

Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte clone.

1996 • 205 citations

IL-15 induces antigen-independent expansion and differentiation of human naive CD8+ T cells in vitro

2003 • 164 citations

Sensory Adaptation in Naive Peripheral CD4 T Cells

2001 • 163 citations

Lipid raft domains and protein networks in T-cell receptor signal transduction

2004 • 142 citations

Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck.

1993 • 132 citations

Autoreactivity, dynamic tuning and selectivity

2001 • 130 citations

T cell homeostasis: Keeping useful T cells alive and live T cells useful

2005 • 124 citations

Role for lipid rafts in regulating interleukin-2 receptor signaling

2001 • 121 citations

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

2007 • 121 citations

IL-2 and IL-15 receptor α-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells

2004 • 119 citations

Peptide Antagonism and T Cell Receptor Interactions with Peptide-MHC Complexes

1998 • 118 citations

Dynamic Tuning of T Cell Reactivity by Self-Peptide–Major Histocompatibility Complex Ligands

2001 • 114 citations

Naive CD8+ T cells differentiate into protective memory-like cells after IL-2–anti–IL-2 complex treatment in vivo

2007 • 108 citations

Towards a cellular definition of CD8+ T-cell memory: the role of CD4+ T-cell help in CD8+ T-cell responses

2004 • 100 citations

Cutting Edge: CD4+ T Cell-Derived IL-2 Is Essential for Help-Dependent Primary CD8+ T Cell Responses

2008 • 93 citations

Self–class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels

2009 • 84 citations

Resting and activated T cells display different requirements for CD8 molecules.

1994 • 64 citations

Cytokine Signals in T-Cell Homeostasis

2005 • 55 citations

Quantitative differences in lipid raft components between murine CD4+ and CD8+ T cells.

2004 • 50 citations

Attenuation of Interleukin 2 Signal in the Spleen Cells of Complex Ganglioside-lacking Mice

1999 • 50 citations

The Lymphopenic Environment of CD132 (Common γ-Chain)-Deficient Hosts Elicits Rapid Homeostatic Proliferation of Naive T Cells via IL-15

2008 • 41 citations

T helper cells, IL-2 and the generation of cytotoxic T-cell responses

2002 • 41 citations

A biophysical approach to IL-2 and IL-15 receptor function: Localization, conformation and interactions

2008 • 40 citations

Differential localization of IL-2- and -15 receptor chains in membrane rafts of human T cells

2002 • 37 citations

CD8 T Cell Sensory Adaptation Dependent on TCR Avidity for Self-Antigens

2005 • 22 citations

LFA-1-dependent Ca2+ Entry following Suboptimal T Cell Receptor Triggering Proceeds without Mobilization of Intracellular Ca2+

2009 • 11 citations