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Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells

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A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles.

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Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

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A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation

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Vacuolar Import of Proteins and Organelles From The Cytoplasm

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Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.

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The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.

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Platelet-Derived Growth Factor Receptor Association with Na⁺/H⁺ Exchanger Regulatory Factor Potentiates Receptor Activity

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Coexpression of platelet-derived growth factor (PDGF) and PDGF-receptor genes by primary human astrocytomas may contribute to their development and maintenance.

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Molecular response of human glioblastoma multiforme cells to ionizing radiation: cell cycle arrest, modulation of cyclin-dependent kinase inhibitors, and autophagy

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Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells.

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PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF

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Malignant epithelial cells in primary human lung carcinomas coexpress in vivo platelet-derived growth factor (PDGF) and PDGF receptor mRNAs and their protein products.

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Differences in substrate specificities of alpha and beta platelet-derived growth factor (PDGF) receptors. Correlation with their ability to mediate PDGF transforming functions

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Platelet-derived Growth Factor-dependent Cellular Transformation Requires Either Phospholipase Cγ or Phosphatidylinositol 3 Kinase

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Demonstration of an activated platelet-derived growth factor autocrine pathway and its role in human tumor cell proliferation in vitro.

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Dominant-Negative Mutants of Platelet-Derived Growth Factor Revert the Transformed Phenotype of Human Astrocytoma Cells

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