Tumor Specific VEGF-A and VEGFR2/KDR Protein are Co-expressed in Breast Cancer

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Validation of Tissue Microarray Technology in Breast Carcinoma

2000 • 800 citations

Tissue Microarrays for Rapid Linking of Molecular Changes to Clinical Endpoints

2001 • 555 citations

VEGFs, receptors and angiogenesis

1999 • 523 citations

Prognostic Significance of Vascular Endothelial Growth Factor Protein in Node-Negative Breast Carcinoma

1997 • 503 citations

Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma.

1994 • 473 citations

Tumor angiogenesis in breast cancer: Its importance as a prognostic indicator and the association with vascular endothelial growth factor expression

1995 • 376 citations

Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast.

1999 • 361 citations

Vascular endothelial growth factor (VEGF) in breast cancer: comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen.

2000 • 336 citations

Vascular endothelial growth factor is of high prognostic value in node-negative breast carcinoma.

1998 • 276 citations

Prognostic value of estrogen receptors in primary breast cancer

1979 • 270 citations

Correlation of Vascular Endothelial Growth Factor Content With Recurrences, Survival, and First Relapse Site in Primary Node-Positive Breast Carcinoma After Adjuvant Treatment

2000 • 255 citations

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells.

1997 • 225 citations

Markers of tumor angiogenesis and proteolysis independently define high- and low-risk subsets of node-negative breast cancer patients.

1998 • 220 citations

Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status

1996 • 198 citations

Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops

1998 • 175 citations

Expresson of Vascular Endothelial Growth Factor, Its Receptors (FLT-1, KDR) and TSP-1 Related to Microvessel Density and Patient Outcome in Vertical Growth Phase Melanomas

2001 • 154 citations

Signaling properties of VEGF receptor-1 and -2 homo- and heterodimers

2001 • 146 citations

Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells

1994 • 144 citations

Why do so many prognostic factors fail to pan out?

1992 • 135 citations

Vascular endothelial growth factor and platelet-derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer.

1995 • 122 citations

Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy.

1999 • 117 citations

Molecular mediators of tumor angiogenesis: Enhanced expression and activation of vascular endothelial growth factor receptor KDR in primary breast cancer

1999 • 106 citations

Estrogen receptors and long-term prognosis in breast cancer

1984 • 90 citations

The prognostic value of vascular endothelial growth factor in 574 node-negative breast cancer patients who did not receive adjuvant systemic therapy

2002 • 89 citations

Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in estrogen receptor negative tumors

2001 • 75 citations

Does vascular endothelial growth factor (VEGF) predict local relapse and survival in radiotherapy-treated node-negative breast cancer?

1999 • 64 citations

Factors influencing the prognostic role of oestrogen and progesterone receptor levels in breast cancer—results of the analysis of 670 patients with 11 years of follow-up

2002 • 60 citations

Prognostic significance of p53, angiogenesis, and other conventional features in operable breast cancer: subanalysis in node-positive and node-negative patients.

1998 • 59 citations

Immunohistochemical Measurement of Tumor Vascular Endothelial Growth Factor in Breast Cancer

2000 • 30 citations