Nitric oxide inhibits the secretion of T‐helper 1‐ and T‐helper 2‐associated cytokines in activated human T cells‘pa

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

1988 • 2,865 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Lymphokine Production by Human T Cells in Disease States

1994 • 1,351 citations

Altered immune responses in mice lacking inducible nitric oxide synthase

1995 • 1,296 citations

Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.

1992 • 1,040 citations

Detection of intracellular cytokines by flow cytometry

1993 • 992 citations

Nitric oxide and asthmatic inflammation

1995 • 514 citations

The Biochemical Pathways of Nitric Oxide Formation from Nitrovasodilators

1991 • 478 citations

Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.

1991 • 436 citations

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin.

1992 • 428 citations

Regulation of the immune response by nitric oxide differentially produced by T helper type 1 and T helper type 2 cells

1994 • 377 citations

Activated murine macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms.

1994 • 372 citations

House dust mite-specific T cells in the skin of subjects with atopic dermatitis: Frequency and lymphokine profile in the allergen patch test

1992 • 278 citations

Differential Expression of iNOS and cNOS mRNA in Human Vascular Smooth Muscle Cells and Endothelial Cells under Normal and Inflammatory Conditions

1993 • 238 citations

Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones.

1990 • 218 citations

Hydrogen peroxide as a potent activator of T lymphocyte functions

1995 • 217 citations

Nitric oxide synthase: MRNA expression of different isoforms in human monocytes/macrophages

1994 • 215 citations

Quantification of nitrite and nitrate in human urine and plasma as pentafluorobenzyl derivatives by gas chromatography—mass spectrometry using their 15N-labelled analogs

1994 • 124 citations

Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide

1994 • 118 citations

Human polymorphonuclear leukocytes lack detectable nitric oxide synthase activity.

1994 • 107 citations

Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors

1994 • 97 citations

Interleukin‐4 and interleukin‐5 are rarely co‐expressed by human T cells

1995 • 79 citations

Nitric oxide synthase: expression of the endothelial, Ca²⁺/calmodulin‐dependent isoform in human B and T lymphocytes

1996 • 79 citations

Differential regulation of cytokine production by nitric oxide.

1993 • 45 citations

Rp-8-Br-guanosine-3′,5′-cyclic monophosphorothioate inhibits relaxation elicited by nitroglycerin in rabbit aorta

1994 • 21 citations

IL-10 secretion of allergen-specific skin-derived T cells correlates positively with that of the Th2 cytokines IL-4 and IL-5*

1994 • 19 citations