Intronic Enhancer Activity of the Eosinophil-derived Neurotoxin (RNS2) and Eosinophil Cationic Protein (RNS3) Genes Is Mediated by an NFAT-1 Consensus Binding Sequence

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

NF-AT components define a family of transcription factors targeted in T-cell activation

1994 • 573 citations

Transmission of Signals from the T Lymphocyte Antigen Receptor to the Genes Responsible for Cell Proliferation and Immune Function: The Missing Link

1990 • 517 citations

Nuclear factor of activated T cells contains Fos and Jun

1992 • 495 citations

Isolation of the Cyclosporin-Sensitive T Cell Transcription Factor NFATp

1993 • 415 citations

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

1995 • 383 citations

NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs.

1993 • 293 citations

Cloning and sequencing of the intronless gene for angiogenin, a human angiogenesis factor

1985 • 273 citations

Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc.

1993 • 245 citations

Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter.

1993 • 202 citations

The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer.

1993 • 201 citations

Multiple closely-linked NFAT/octamer and HMG I(Y) binding sites are part of the interleukin-4 promoter

1993 • 191 citations

Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family.

1989 • 190 citations

A common factor regulates both Th1- and Th2-specific cytokine gene expression.

1994 • 151 citations

Direct Demonstration of NFATp Dephosphorylation and Nuclear Localization in Activated HT-2 Cells Using a Specific NFATp Polyclonal Antibody

1995 • 134 citations

The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

1993 • 131 citations

Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily.

1993 • 131 citations

Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4

1994 • 125 citations

Cyclosporin-a sensitive induction of NF-AT in murine B cells

1994 • 124 citations

Expression of the transcription factor NFATp in a neuronal cell line and in the murine nervous system.

1994 • 123 citations

Eosinophils. A comprehensive review and guide to the scientific and medical literature

1989 • 123 citations

Definition of cis-Regulatory Elements of the Mouse Interleukin-5 Gene Promoter

1995 • 100 citations

The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer

1991 • 99 citations

Structure and chromosome localization of the human eosinophil-derived neurotoxin and eosinophil cationic protein genes: Evidence for intronless coding sequences in the ribonuclease gene superfamily

1990 • 99 citations

Lactoferrin gene promoter: structural integrity and nonexpression in HL60 cells

1992 • 86 citations

The Human gp39 Promoter

1995 • 86 citations

Eosinophils : biological and clinical aspects

1993 • 80 citations

Multiple signals are required for function of the human granulocyte-macrophage colony-stimulating factor gene promoter in T cells.

1995 • 74 citations

Neutrophil-specific granule deficiency includes eosinophils

1993 • 58 citations

Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiency.

1989 • 58 citations

Structure of the bovine pancreatic ribonuclease gene: the unique intervening sequence in the 5′ untranslated region contains a promoter-like element

1988 • 47 citations

p21ras links Fc epsilon RI to NF-AT family member in mast cells. The AP3-like factor in this cell type is an NF-AT family member.

1995 • 38 citations

Enhanced Expression of the Eosinophil-derived Neurotoxin Ribonuclease (RNS2) Gene Requires Interaction between the Promoter and Intron

1996 • 36 citations

The proximal promoter of the IL-4 gene is composed of multiple essential regulatory sites that bind at least two distinct factors.

1995 • 35 citations

Cloning and sequence analysis of the human gene encoding eosinophil major basic protein

1990 • 33 citations

Isolation of the murine ribonuclease geneRib-1: structure and tissue specific expression of pancreas and parotid gland

1991 • 12 citations