Cell proliferation and apoptosis during prostatic tumor xenograft involution and regrowth after castration

Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgen-independent prostate cancer.

1992 • 1,063 citations

Important Advances in Oncology

1991 • 768 citations

Activation of Programmed Cell Death in the Rat Ventral Prostate after Castration*

1988 • 730 citations

Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview

1992 • 600 citations

Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

1993 • 597 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Internucleosomal DNA Cleavage Should not be the Sole Criterion for Identifying Apoptosis

1992 • 462 citations

Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma.

1981 • 382 citations

Important advances in oncology 1994

1994 • 282 citations

Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration

1989 • 266 citations

Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle.

1992 • 245 citations

Apoptosis and Its Role in Human Disease

1994 • 232 citations

Serum prostate specific antigen levels in mice bearing human prostate LNCaP tumors are determined by tumor volume and endocrine and growth factors.

1992 • 228 citations

The effect of estrone-progesterone treatment on cell proliferation kinetics of hormone-dependent GR mouse mammary tumors.

1975 • 218 citations

Cell death via apoptosis and its relationship to growth, development and differentiation of both tumour and normal cells.

1990 • 216 citations

Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation.

1993 • 201 citations

Activation of a Ca²⁺−Mg²⁺‐dependent endonuclease as an early event in castration‐induced prostatic cell death

1988 • 176 citations

Pathologic changes associated with androgen deprivation therapy for prostate cancer

1991 • 161 citations

Regulation of prostate growth

1991 • 159 citations

Castration therapy rapidly induces apoptosis in a minority and decreases cell proliferation in a majority of human prostatic tumors.

1995 • 158 citations

Prostate Specific Antigen in Hormonally Treated Stage D2 Prostate Cancer: Is it always an Accurate Indicator of Disease Status?

1991 • 124 citations

Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer

1993 • 123 citations

Prostatic cell lineage markers: Emergence of BCL2+ cells of human prostate cancer xenograft LuCaP 23 following castration

1996 • 81 citations

Castration induces apoptosis in the ventral prostate but not in an androgen-sensitive prostatic adenocarcinoma in the rat.

1994 • 54 citations

Prostatic tumor regrowth after initially successful castration therapy may be related to a decreased apoptotic cell death rate.

1994 • 44 citations

Castration rapidly results in a major reduction in epithelial cell numbers in the rat prostate, but not in the highly differentiated dunning R3327 prostatic adenocarcinoma

1993 • 41 citations

Advances and controversies in the study of programmed cell death/apoptosis in the development of and therapy for cancer

1994 • 40 citations