Castration rapidly results in a major reduction in epithelial cell numbers in the rat prostate, but not in the highly differentiated dunning R3327 prostatic adenocarcinoma

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Activation of Programmed Cell Death in the Rat Ventral Prostate after Castration*

1988 • 730 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma.

1981 • 382 citations

Cascade Induction of c-fos, c-myc, and Heat Shock 70K Transcripts during Regression of the Rat Ventral Prostate Gland

1988 • 355 citations

Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration

1989 • 266 citations

Androgen‐repressed messages in the rat ventral prostate

1986 • 261 citations

Serum prostate specific antigen levels in mice bearing human prostate LNCaP tumors are determined by tumor volume and endocrine and growth factors.

1992 • 228 citations

Effect of Transforming Growth Factor-β¹on Proliferation and Death of Rat Prostatic Cells*

1990 • 218 citations

Characterization of the Dunning R3327H prostatic adenocarcinoma: an appropriate animal model for prostatic cancer.

1977 • 135 citations

“Thymineless” death in androgen-independent prostatic cancer cells

1989 • 101 citations

Light microscopic morphometric analysis of castration effects in the different lobes of the rat prostate

1988 • 38 citations

Estrogen treatment combined with castration inhibits tumor growth more effectively than castration alone in the dunning R3327 rat prostatic adenocarcinoma

1990 • 34 citations

Urokinase- and tissue-type plasminogen activators are suppressed by cortisol in the involuting prostate of castrated rats

1990 • 33 citations

Androgen‐independent epithelial cells of the rat ventral prostate

1988 • 30 citations

Programmed cell death as a new target for prostatic cancer therapy.

1991 • 30 citations

Histological changes in dunning prostate tumors and testes of rats treated with LH‐RH antagonist SB‐75

1991 • 24 citations

A morphometric analysis of rat ventral prostate in organ culture

1983 • 23 citations

Antiestrogens do not counteract the inhibitory effect of estradiol‐17β on the growth of the dunning R3327 prostatic adenocarcinoma

1988 • 17 citations