Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation.

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

A Controlled Trial of Leuprolide with and without Flutamide in Prostatic Carcinoma

1989 • 1,494 citations

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1992 • 871 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

Activation of Programmed Cell Death in the Rat Ventral Prostate after Castration*

1988 • 730 citations

High levels of p53 protein in UV-irradiated normal human skin.

1993 • 689 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Induction of the TRPM-2 gene in cells undergoing programmed death.

1989 • 466 citations

Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles.

1991 • 440 citations

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

1989 • 417 citations

Cascade Induction of c-fos, c-myc, and Heat Shock 70K Transcripts during Regression of the Rat Ventral Prostate Gland

1988 • 355 citations

Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement

1987 • 348 citations

p53-mediated cell death: relationship to cell cycle control.

1993 • 339 citations

Antagonistic effect of androgen on prostatic cell death

1984 • 339 citations

Deletion of cells by apoptosis during castration-induced involution of the rat prostate

1973 • 285 citations

Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration

1989 • 266 citations

Changes in cyclin/proliferating cell nuclear antigen distribution during DNA repair synthesis.

1988 • 248 citations

Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle.

1992 • 245 citations

Activation of a Ca²⁺−Mg²⁺‐dependent endonuclease as an early event in castration‐induced prostatic cell death

1988 • 176 citations

Androgen Regulation of Programmed Death of Normal and Malignant Prostatic Cells

1992 • 168 citations

Cell proliferation studies in the rat prostate: II. The effects of castration and androgen‐induced regeneration upon basal and secretory cell proliferation

1987 • 164 citations

Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation

1984 • 161 citations

Programmed death of nonproliferating androgen-independent prostatic cancer cells.

1991 • 159 citations

The Influence of Hormonal Therapy on Survival of Men with Advanced Prostatic Cancer

1982 • 141 citations

Cellular response to androgen depletion and repletion in the rat ventral prostate: Autoradiography and morphometric analysis

1985 • 138 citations

Calcium channel antagonists delay regression of androgen‐dependent tissues and suppress gene activity associated with cell death

1988 • 128 citations

Role of calcium in the programmed death of rat prostatic glandular cells

1990 • 115 citations

Non-hormone chemotherapy for prostate cancer: principles of treatment and application to the testing of new drugs.

1988 • 111 citations

“Thymineless” death in androgen-independent prostatic cancer cells

1989 • 101 citations

p53-Mediated Cell Death: Relationship to Cell Cycle Control

1993 • 98 citations

Apoptosis of rat thymocytes triggered by prednisolone, camptothecin, or teniposide is selective to G0 cells and is prevented by inhibitors of proteases.

1992 • 75 citations

Tracer dose and availability time of thymidine and bromodeoxyuridine: application of bromodeoxyuridine in cell kinetic studies

1990 • 70 citations

Proliferative Activity of Benign Human Prostate, Prostatic Adenocarcinoma and Seminal Vesicle Evaluated by Thymidine Labeling

1982 • 70 citations

S‐phase fraction of human prostate adenocarcinoma studied with in vivo bromodeoxyuridine labeling

1990 • 60 citations

Induction of the TRPM-2 Gene in Cells Undergoing Programmed Death

1989 • 53 citations

Statistical confirmation that immunofluorescent detection of DNA repair in human fibroblasts by measurement of bromodeoxyuridine incorporation is stoichiometric and sensitive

1993 • 47 citations

Castration‐induced changes in morphology, androgen levels, and proliferative activity of human prostate cancer tissue grown in athymic nude mice

1993 • 46 citations

Die Regression der Rattenprostata nach Kastration

1981 • 22 citations

[Histological and cell kinetic studies of the growth of rat prostate of various ages].

1981 • 1 citations