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Transcriptional regulation of the MHC class Ib genes HLA-E, HLA-F, and HLA-G

Data up to Jan 2025

Published2000
Citations125
References31

Total Citations Per Year

Abstract

References (31)

Functions of nonclassical MHC and non-MHC-encoded class I molecules

1999 • 211 citations

The functionality of HLA‐G is emerging

1999 • 177 citations

Structure and function of the human MHC class Ib molecules HLA‐E, HLA‐F and HLA‐G

1998 • 173 citations

Regulation of MHC class I and II gene transcription: differences and similarities

1998 • 139 citations

Transactivation of classical and nonclassical HLA class I genes through the IFN-stimulated response element.

1999 • 129 citations

The RFX Complex Is Crucial for the Constitutive and CIITA-Mediated Transactivation of MHC Class I and β2-Microglobulin Genes

1998 • 113 citations

Transactivation of Classical and Nonclassical HLA Class I Genes Through the IFN-Stimulated Response Element

1999 • 112 citations

The role of enhancer A in the locus-specific transactivation of classical and nonclassical HLA class I genes by nuclear factor kappa B.

1998 • 110 citations

HLA-F Is a Predominantly Empty, Intracellular, TAP-Associated MHC Class Ib Protein with a Restricted Expression Pattern

2000 • 107 citations

Shared regulatory elements in the promoters of MHC class I and class II genes

1998 • 105 citations

Methylation of Class IItrans-Activator Promoter IV: A Novel Mechanism of MHC Class II Gene Control

2000 • 95 citations

The Role of Enhancer A in the Locus-Specific Transactivation of Classical and Nonclassical HLA Class I Genes by Nuclear Factor κB

1998 • 92 citations

HLA and Pregnancy: The Paradox of the Fetal Allograft

1998 • 87 citations

Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory regions of HLA class II genes.

1997 • 83 citations

Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta.

1995 • 83 citations

Antigen-presenting function(s) of the non-classical HLA-E, -F and -G class I molecules: the beginning of a story

1996 • 80 citations

Interferon-γ Induction of the Human Leukocyte Antigen-E Gene Is Mediated through Binding of a Complex Containing STAT1α to a Distinct Interferon-γ-responsive Element

1996 • 76 citations

Lack of CIITA expression is central to the absence of antigen presentation functions of trophoblast cells and is caused by methylation of the IFN-γ inducible promoter (PIV) of CIITA

2000 • 73 citations

Absence of MHC class II antigen expression in trophoblast cells results from a lack of class II transactivator (CIITA) gene expression

1998 • 67 citations

HLA-E is the only class I gene that escapes CpG methylation and is transcriptionally active in the trophoblast-derived human cell line JAR

1993 • 64 citations

Recent developments in the human maternal-fetal immune interaction

1991 • 64 citations

Extraembryonic expression of the human MHC class I gene HLA-G in transgenic mice. Evidence for a positive regulatory region located 1 kilobase 5' to the start site of transcription.

1993 • 61 citations

MHC Class II Gene Silencing in Trophoblast Cells Is Caused by Inhibition of CIITA Expression

1998 • 52 citations

Interferon Regulatory Factor 1 Mediates the Interferon-γ Induction of the Human Immunoproteasome Subunit Multicatalytic Endopeptidase Complex-like 1

1999 • 43 citations

The regulation of HLA class I expression: is HLA-G the odd one out?

1999 • 39 citations

Assembly of functional regulatory complexes on MHC class II promoters in vivo

1997 • 36 citations

Repression of Major Histocompatibility Complex Genes by a Human Trophoblast Ribonucleic Acid

1999 • 28 citations

HLA‐G Transgenic Mice: A Model for Studying Expression and Function at the Maternal/Fetal Interface

1995 • 27 citations

DOMINANT NEGATIVE SUPPRESSION OF MAJOR HISTOCOMPATIBILITY COMPLEX GENES OCCURS IN TROPHOBLASTS1

1999 • 18 citations

Transcriptional regulation of HLA-G

1999 • 17 citations

HLA-G transgenic mice

1999 • 9 citations

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Transcriptional regulation of the MHC class Ib genes HLA-E, HLA-F, and HLA-G (2000) – Human Immunology | Metascience Observatory Explorer