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Structure and function of the human MHC class Ib molecules HLA‐E, HLA‐F and HLA‐G

Data up to Jan 2025

Published1998
Citations173
References50

Total Citations Per Year

Abstract

References (50)

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HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

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1989 • 1,207 citations

Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 Å resolution

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HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A

1998 • 998 citations

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1995 • 817 citations

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1998 • 706 citations

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1990 • 693 citations

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1995 • 599 citations

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1992 • 522 citations

A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment.

1987 • 515 citations

The human major histocompatibility complex class Ib molecule HLA‐E binds signal sequence‐derived peptides with primary anchor residues at positions 2 and 9

1997 • 489 citations

Protection from Natural Killer Cell-Mediated Lysis by HLA-G Expression on Target Cells

1996 • 489 citations

Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.

1995 • 479 citations

Crystal structure of the complex between human CD8αα and HLA-A2

1997 • 471 citations

A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4.

1994 • 365 citations

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1995 • 320 citations

Identification of a Thymic Epithelial Cell Subset Sharing Expression of the Class Ib HLA-G Molecule with Fetal Trophoblasts

1997 • 296 citations

Identification of a tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen

1994 • 275 citations

TAP- and tapasin-dependent HLA-E surface expression correlates with the binding of an MHC class I leader peptide

1998 • 275 citations

Evidence for the expression of HLAA-C class I mRNA and protein by human first trimester trophoblast.

1996 • 259 citations

Antigen Presentation by Major Histocompatibility Complex Class I-B Molecules

1994 • 248 citations

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

1989 • 233 citations

Transfer and expression of three cloned human non-HLA-A,B,C class I major histocompatibility complex genes in mutant lymphoblastoid cells.

1988 • 226 citations

Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue

1990 • 224 citations

Structural Features Impose Tight Peptide Binding Specificity in the Nonclassical MHC Molecule HLA-E

1998 • 206 citations

Nonclassical HLA-G molecules are classical peptide presenters

1996 • 201 citations

Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element.

1990 • 200 citations

Resistance of HLA-G and HLA-A2 Transfectants to Lysis by Decidual NK Cells

1994 • 179 citations

The CD94/NKG2-A inhibitory receptor complex is involved in natural killer cell-mediated recognition of cells expressing HLA-G1.

1997 • 159 citations

CD94/NKG2 is the predominant inhibitory receptor involved in recognition of HLA-G by decidual and peripheral blood NK cells.

1997 • 140 citations

Cell-cell adhesion mediated by CD8 and human histocompatibility leukocyte antigen G, a nonclassical major histocompatibility complex class 1 molecule on cytotrophoblasts.

1991 • 128 citations

The HLA class I gene family includes at least six genes and twelve pseudogenes and gene fragments.

1992 • 126 citations

HLA Class I Chromosomal Region, Genes, and Products: Facts and Questions

1994 • 123 citations

Down-regulation of the class I HLA heterodimer and beta2-microglobulin on the surface of cells infected with cytomegalovirus

1992 • 111 citations

HLA-G polymorphisms in African Americans.

1994 • 105 citations

Phenotypic and functional cellular differences between human CD3- decidual and peripheral blood leukocytes.

1994 • 103 citations

Dominance of a single peptide bound to the class I(B) molecule, Qa-1b.

1997 • 103 citations

The MHC E locus in macaques is polymorphic and is conserved between macaques and humans

1995 • 90 citations

The mRNA of a human class I gene HLA G/HLA 6.0 exhibits a restricted pattern of expression

1990 • 80 citations

Antigen-presenting function(s) of the non-classical HLA-E, -F and -G class I molecules: the beginning of a story

1996 • 80 citations

Qa‐1 interaction and T cell recognition of the Qa‐1 determinant modifier peptide

1997 • 63 citations

Impaired intracellular transport and cell surface expression of nonpolymorphic HLA-E: evidence for inefficient peptide binding.

1992 • 61 citations

A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site.

1993 • 42 citations

Peptide binding to the class Ib molecule, Qa-1b.

1997 • 36 citations

A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site.

1993 • 35 citations

Analysis of T cell receptors specific for recognition of class IB antigens.

1993 • 33 citations

Production, crystallization, and preliminary X‐ray analysis of the human MHC class Ib molecule HLA‐E

1998 • 32 citations

High polymorphism of Mhc‐E locus in non‐human primates: alleles with identical exon 2 and 3 are found in two different species

1997 • 26 citations

An identification of the HLA-F null allele in Japanese

1997 • 10 citations

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Structure and function of the human MHC class Ib molecules HLA‐E, HLA‐F and HLA‐G (1998) – Immunological Reviews | Metascience Observatory Explorer