Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

Genetic instabilities in human cancers

1998 • 4,165 citations

The Genetics and Biology of Drosophila

1978 • 3,910 citations

Applying the principles of stem-cell biology to cancer

2003 • 1,623 citations

Self-renewal and solid tumor stem cells

2004 • 894 citations

Spatial and temporal patterns of neurogenesis in the central nervous system of Drosophila melanogaster

1988 • 720 citations

Centrosome defects and genetic instability in malignant tumors.

1998 • 583 citations

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

2004 • 528 citations

Malignant Neoplasms of Genetic Origin in Drosophila melanogaster

1978 • 441 citations

Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis.

2001 • 383 citations

Centrosome abnormalities and chromosome instability occur together in pre-invasive carcinomas.

2003 • 374 citations

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

2004 • 333 citations

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

2000 • 332 citations

Diverse mechanisms regulate stem cell self-renewal

2004 • 330 citations

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

2000 • 326 citations

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

2003 • 294 citations

Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry

2003 • 258 citations

Genes controlling essential cell-cycle functions in Drosophila melanogaster.

1989 • 255 citations

Inactivation of Numb and Numblike in Embryonic Dorsal Forebrain Impairs Neurogenesis and Disrupts Cortical Morphogenesis

2003 • 217 citations

Gamma-tubulin is required for the structure and function of the microtubule organizing centre in Drosophila neuroblasts.

1995 • 179 citations

The centrosome cycle

2002 • 163 citations

Developmental capacities of benign and malignant neoplasms ofDrosophila

1974 • 146 citations

Konstanz, Wechsel und Typus der Determination und Differenzierung in Zellen aus männlichen Genitalanlagen von Drosophila melanogaster nach Dauerkultur in vivo

1966 • 139 citations

Drosophila in cancer research: the first fifty tumor suppressor genes

1994 • 109 citations

Übertragung und Änderung der Determinations-qualitäten in Antennenscheiben-Kulturen vonDrosophila melanogaster

1966 • 106 citations

Tumor suppressors: Linking cell polarity and growth control

2000 • 92 citations

Neoplasms in mutant and cultured wild-tupe tissues of Drosophila.

1969 • 89 citations

Asymmetric localization and function of cell-fate determinants: a fly’s view

2004 • 85 citations

Patterns of Cell Division and Expression of Asymmetric Cell Fate Determinants in Postembryonic Neuroblast Lineages of Drosophila

2001 • 75 citations

Asymmetric division of Drosophila neural progenitors

2002 • 50 citations

Cell heredity and changes of determination in cultures of antenna imaginal discs in Drosophila melanogaster

1966 • 28 citations

Proliferation and Polarity in Breast Cancer: Untying the Gordian Knot

2005 • 21 citations