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MRL/Mp CD4+,CD25− T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus

Data up to Jan 2025

Published2005
Citations131
References19

Total Citations Per Year

Abstract

References (19)

Quantification of regulatory T cells in patients with systemic lupus erythematosus

2003 • 417 citations

Systemic Lupus Erythematosus

1994 • 407 citations

The major murine systemic lupus erythematosus susceptibility locus,Sle1, is a cluster of functionally related genes

2001 • 332 citations

Decreased CD4+CD25+ T Cells in Peripheral Blood of Patients with Systemic Lupus Erythematosus

2004 • 286 citations

Dynamics of Pathogenic and Suppressor T Cells in Autoimmune Diabetes Development

2003 • 243 citations

Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupuslike disease in syngeneic mice.

1996 • 233 citations

Spontaneous Autoimmunity in 129 and C57BL/6 Mice—Implications for Autoimmunity Described in Gene-Targeted Mice

2004 • 187 citations

Alterations in Lipid Raft Composition and Dynamics Contribute to Abnormal T Cell Responses in Systemic Lupus Erythematosus

2004 • 181 citations

Altered lipid raft–associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus

2004 • 165 citations

Altered lipid raft–associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus

2004 • 164 citations

Abnormal T cell signal transduction in systemic lupus erythematosus

2002 • 142 citations

Multiple Lupus Susceptibility Loci Map to Chromosome 1 in BXSB Mice

1998 • 134 citations

Resistance to CD4+CD25+ Regulatory T Cells and TGF-β in Cbl-b−/− Mice

2004 • 120 citations

Cd4+ T Cells from Lupus-Prone Mice Are Hyperresponsive to T Cell Receptor Engagement with Low and High Affinity Peptide Antigens

2001 • 116 citations

Regulatory Defects in Cbl and Mitogen-Activated Protein Kinase (Extracellular Signal-Related Kinase) Pathways Cause Persistent Hyperexpression of CD40 Ligand in Human Lupus T Cells

2000 • 93 citations

A deficiency of CD4+ CD25+ T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen

2004 • 79 citations

CD4+ T Cells from Lupus-Prone Mice Avoid Antigen-Specific Tolerance Induction In Vivo

2003 • 44 citations

T cell abnormalities in human and mouse lupus: intrinsic and extrinsic

2003 • 41 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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MRL/Mp CD4+,CD25− T cells show reduced sensitivity to suppression by CD4+,CD25+… (2005) – Arthritis & Rheumatism | Metascience Observatory Explorer