Human N-ras: cDNA cloning and gene structure

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A simple and very efficient method for generating cDNA libraries

1983 • 4,606 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

High-Efficiency Cloning of Full-Length cDNA

1982 • 1,309 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

1981 • 795 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

1982 • 706 citations

Speculations on RNA splicing

1981 • 639 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1983 • 553 citations

Structure and activation of the human N-ras gene

1983 • 538 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

1982 • 494 citations

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1

1983 • 441 citations

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

1984 • 435 citations

Transforming activity of human tumor DNAs.

1981 • 374 citations

Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene

1983 • 360 citations

The HL-60 transforming sequence: A ras oncogene coexisting with altered myc genes in hematopoietic tumors

1983 • 341 citations

Adenosine deaminase: characterization and expression of a gene with a remarkable promoter.

1985 • 329 citations

Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses.

1982 • 309 citations

Analysis of the transforming potential of the human H-ras gene by random mutagenesis.

1984 • 290 citations

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.

1982 • 268 citations

Altered gene products are associated with activation of cellular rasK genes in human lung and colon carcinomas

1983 • 175 citations

Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype.

1983 • 172 citations

Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080.

1984 • 124 citations

Effect of the 21-bp repeat upstream element on in vitro transcription from the early and late SV40 promoters.

1984 • 87 citations

Sequence and structure of the coding region of the human H-ras-1 gene from T24 bladder carcinoma cells.

1983 • 74 citations

Transcription of the Mouse Dihydrofolate Reductase Gene Proceeds Unabated Through Seven Polyadenylation Sites and Terminates Near a Region of Repeated DNA

1984 • 63 citations

Activation of N-ras gene in bone marrow cells from a patient with acute myeloblastic leukaemia

1984 • 58 citations

The human c-Ha-ras2 is a processed pseudogene inactivated by numerous base substitutions

1984 • 32 citations