Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

Lambdoid phages that simplify the recovery of in vitro recombinants

1977 • 779 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

1982 • 706 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

Structure and activation of the human N-ras gene

1983 • 538 citations

Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

1982 • 494 citations

Oncogenes in solid human tumours

1982 • 467 citations

Human-tumor-derived cell lines contain common and different transforming genes

1981 • 455 citations

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1

1983 • 441 citations

A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

1983 • 396 citations

Predicted nucleotide-binding properties of p21 protein and its cancer-associated variant

1983 • 390 citations

Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

1983 • 385 citations

A bacteriophage lambda vector for cloning large DNA fragments made with several restriction enzymes

1980 • 379 citations

Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1

1983 • 377 citations

Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene

1983 • 360 citations

Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

1980 • 356 citations

ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

1983 • 345 citations

The HL-60 transforming sequence: A ras oncogene coexisting with altered myc genes in hematopoietic tumors

1983 • 341 citations

Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses.

1982 • 309 citations

Nucleotide Sequence of the p21 Transforming Protein of Harvey Murine Sarcoma Virus

1982 • 272 citations

Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus

1982 • 256 citations

Three different human tumor cell lines contain different oncogenes

1981 • 245 citations

Characterization of a human colon/lung carcinoma oncogene

1983 • 208 citations

Stage-specific transforming genes of human and mouse B- and T-lymphocyte neoplasms

1982 • 175 citations

Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype.

1983 • 172 citations

Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus

1982 • 151 citations

A transforming gene present in human sarcoma cell lines

1982 • 114 citations

Novel use of synthetic oligonucleotide insertion mutants for the study of homologous recombination in mammalian cells.

1983 • 80 citations

Prediction of the three-dimensional structure of the transforming region of the EJ/T24 human bladder oncogene product and its normal cellular homologue.

1983 • 75 citations

Activation of N-ras gene in bone marrow cells from a patient with acute myeloblastic leukaemia

1984 • 58 citations

Localisation of the human N-ras oncogene to chromosome 1cen - p21 by in situ hybridisation.

1983 • 44 citations

The human c-Ha-ras2 is a processed pseudogene inactivated by numerous base substitutions

1984 • 32 citations

Immunocytochemical localization in normal and transformed human cells in tissue culture using a monoclonal antibody to the src protein of the Harvey strain of Murine Sarcoma Virus

1983 • 28 citations