Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1993 • 1,267 citations

The Tumor Necrosis Factor Ligand and Receptor Families

1996 • 1,239 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

The implications of angiogenesis for the biology and therapy of cancer metastasis

1994 • 1,120 citations

Matrix metalloproteinases in tumor invasion and metastasis

2000 • 820 citations

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

1991 • 815 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation

1998 • 715 citations

Involvement of Interleukin-8, Vascular Endothelial Growth Factor, and Basic Fibroblast Growth Factor in Tumor Necrosis Factor Alpha-Dependent Angiogenesis

1997 • 686 citations

Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.

1991 • 576 citations

Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice

2003 • 532 citations

Induction of Vascular Endothelial Growth Factor by Tumor Necrosis Factor α in Human Glioma Cells

1996 • 459 citations

Dual role of tumor necrosis factor-alpha in angiogenesis.

1992 • 342 citations

Interactions between cancer cells and the endothelium in metastasis

2000 • 282 citations

Tumor Necrosis Factor-α Regulates Expression of Vascular Endothelial Growth Factor Receptor-2 and of Its Co-receptor Neuropilin-1 in Human Vascular Endothelial Cells

1998 • 262 citations

Platelet-derived Growth Factor Signaling and Human Cancer

2003 • 262 citations

Enhancement of human hepatocyte growth factor production by interleukin-1 alpha and -1 beta and tumor necrosis factor-alpha by fibroblasts in culture.

1993 • 224 citations

In vivo angiogenic activity and hypoxia induction of heterodimers of placenta growth factor/vascular endothelial growth factor.

1996 • 220 citations

Enhancement of experimental metastasis by tumor necrosis factor.

1993 • 198 citations

TNFerade Biologic, an Adenovector With a Radiation-Inducible Promoter, Carrying the Human Tumor Necrosis Factor Alpha Gene: A Phase I Study in Patients With Solid Tumors

2004 • 197 citations

Comparison of the efficacy of the tumour necrosis factor blocking agents adalimumab, etanercept, and infliximab when added to methotrexate in patients with active rheumatoid arthritis

2003 • 176 citations

Cells secreting tumour necrosis factor show enhanced metastasis in nude mice

1990 • 154 citations

Paclitaxel liposome aerosol treatment induces inhibition of pulmonary metastases in murine renal carcinoma model.

2001 • 152 citations

Essential roles of tumor necrosis factor receptor p55 in liver metastasis of intrasplenic administration of colon 26 cells.

2002 • 116 citations

Expression of vascular endothelial growth factor and its receptors in multiple myeloma and other hematopoietic malignancies

2001 • 105 citations

Assessment of Differential Cytokine Effects on Angiogenesis Using an in Vivo Model of Cutaneous Wound Repair

1995 • 92 citations

Preparation of specific antibodies against murine IL-1ra and the establishment of IL-1ra as an endogenous regulator of bacteria-induced fulminant hepatitis in mice

1995 • 82 citations

Synergistic effects of combination therapy with human recombinant interleukin-2 and tumor necrosis factor in murine tumor models.

1987 • 82 citations

Pathogenic Roles of Tumor Necrosis Factor Receptor p55–Mediated Signals in Dimethylnitrosamine-Induced Murine Liver Fibrosis

2002 • 66 citations

Promotion of experimental liver metastasis by tumor necrosis factor

1995 • 62 citations

Factors influencing blood supply in wound granuloma quantitated by a new in vivo technique.

1989 • 58 citations

Treating tumor-bearing mice with low-dose gamma-interferon plus tumor necrosis factor alpha to diminish immune suppressive granulocyte-macrophage progenitor cells increases responsiveness to interleukin 2 immunotherapy.

1995 • 33 citations

Phase I Trial of Recombinant Interleukin-2 Followed by Recombinant Tumor Necrosis Factor in Patients with Metastatic Cancer

1992 • 23 citations

Preventive and Antiproliferative Effects of Tumor Necrosis Factor against Experimental Hepatic Metastases of Mouse Colon‐26 Tumor

1989 • 18 citations

Antimetastatic effect of endogenous tumor necrosis factor induced by the treatment of recombinant interferon γ followed by an analogue (GLA-60) to synthetic lipid A subunit

1989 • 17 citations

Protective Activity of Recombinant Murine Tumor Necrosis Factor-α and Interferon-γ Against Experimental Murine Lung Carcinoma Metastases

1990 • 17 citations

Anti‐tumor effect of recombinant murine TNF‐alpha (rmutnfa) given by continuous I.V. infusion as compared to repeated I.V. injections in a rat liver metastasis model

1989 • 11 citations

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