Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes

In silico prediction of protein-protein interactions in human macrophages

2014 • 11,120 citations

Significance analysis of microarrays applied to the ionizing radiation response

2001 • 10,393 citations

Biochemistry and molecular cell biology of diabetic complications

2001 • 8,707 citations

Disruption of IRS-2 causes type 2 diabetes in mice

1998 • 1,766 citations

THE NOD MOUSE: A Model of Immune Dysregulation

2004 • 1,080 citations

Fuel feeds function: energy metabolism and the T-cell response

2005 • 813 citations

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

2005 • 744 citations

STRUCTURE, FUNCTION AND REGULATION OF THE VACUOLAR (H⁺)-ATPase

1997 • 588 citations

Adoptive Transfer of Diabetes Into Immunodeficient NOD-scid/scid Mice: Relative Contributions of CD4+ and CD8+ T-Cells From Diabetic Versus Prediabetic NOD.NON-Thy-1a Donors

1993 • 431 citations

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

2005 • 417 citations

Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis

2005 • 408 citations

FXYD proteins: new regulators of Na-K-ATPase

2006 • 344 citations

NUCLEAR RECEPTORS IN MACROPHAGE BIOLOGY: At the Crossroads of Lipid Metabolism and Inflammation

2004 • 294 citations

An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians.

1998 • 212 citations

The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: Subserving RPGR function and participating in disk morphogenesis

2003 • 211 citations

Glucose Homeostasis and Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred Strains of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1

2004 • 151 citations

Distinct molecular mechanisms for protein sorting within immature secretory granules of pancreatic beta-cells.

1994 • 148 citations

Is Latent Autoimmune Diabetes in Adults Distinct From Type 1 Diabetes or Just Type 1 Diabetes at an Older Age?

2005 • 137 citations

Genetic and pathogenic basis of autoimmune diabetes in NOD mice

1994 • 136 citations

A DNA polymorphism, consistent with gene duplication, correlates with high renin levels in the mouse submaxillary gland

1982 • 126 citations

Thymocyte expression of cathepsin L is essential for NKT cell development

2002 • 110 citations

The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity

1995 • 103 citations

Transgenic rescue implicates β₂-microglobulin as a diabetes susceptibility gene in nonobese diabetic (NOD) mice

2001 • 95 citations

Salivary Gland Cytokine Expression in NOD and Normal BALB/c Mice

1999 • 93 citations

Cathepsin L is essential for onset of autoimmune diabetes in NOD mice

2005 • 84 citations

Elevated levels of cysteine protease activity in saliva and salivary glands of the nonobese diabetic (NOD) mouse model for Sjögren syndrome

1997 • 80 citations

Genetic and endocrine control of renin activity in the submaxillary gland of the mouse

1981 • 71 citations

Evidence of beta cell dysfunction which does not lead on to diabetes: a study of identical twins of insulin dependent diabetics.

1987 • 68 citations

EVOLUTION AND VARIATION OF RENIN GENES IN MICE

1984 • 63 citations

New concepts for the development of autoimmune exocrinopathy derived from studies with the NOD mouse model

1999 • 51 citations

Immune cells, pancreas development, regeneration and type 1 diabetes

2004 • 46 citations

Inhibition of submandibular and lacrimal gland infiltration in nonobese diabetic mice by transgenic expression of soluble TNF-receptor p55.

1996 • 46 citations

Genetic Modifiers of the Age at Diagnosis of Diabetes (MODY3) in Carriers of Hepatocyte Nuclear Factor-1α Mutations Map to Chromosomes 5p15, 9q22, and 14q24

2003 • 43 citations

Mouse Models of Type 1 and Type 2 Diabetes Derived from the Same Closed Colony: Genetic Susceptibility Shared Between Two Types of Diabetes

2004 • 41 citations

Interleukin-1 effect on glycemia in the non-obese diabetic mouse at the pre-diabetic stage

1996 • 38 citations

A Susceptibility Allele From a Non-Diabetes-Prone Mouse Strain Accelerates Diabetes in NOD Congenic Mice

2003 • 33 citations

Beta-cell behaviour during the prediabetic stage. Part II. Non-insulin-dependent and insulin-dependent diabetes mellitus.

1997 • 31 citations

Islet Endocrine-Cell Behavior From Birth Onward in Mice With the Nonobese Diabetic Genetic Background

2001 • 22 citations

The Perks of Balancing Glucose

2001 • 22 citations

Characteristics of Autoimmunity in Type 1 Diabetes and Type 1.5 Overlap With Type 2 Diabetes

2005 • 20 citations

Essential Role for the Lymphostromal Plasma Membrane Ly-6 Superfamily Molecule Thymic Shared Antigen 1 in Development of the Embryonic Adrenal Gland

2002 • 17 citations

High proinsulin levels in late PRE-IDDM stage

1997 • 12 citations

Beta-cell behavior during the prediabetic stage. Part I. Beta-cell pathophysiology.

1997 • 9 citations

Identification of seven loci for static glucokinesis and dynamic glucokinesis in mice

2002 • 8 citations

Antigenic determinants in type 1 diabetes mellitus:

1996 • 6 citations