Control of nucleocytoplasmic transport

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

Major nucleolar proteins shuttle between nucleus and cytoplasm

1989 • 1,113 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor.

1987 • 999 citations

A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo

1989 • 652 citations

Nuclear protein localization

1991 • 570 citations

How proteins enter the nucleus

1991 • 555 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components.

1990 • 510 citations

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

1991 • 501 citations

The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila

1989 • 472 citations

Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function

1989 • 431 citations

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1989 • 417 citations

Monomethylated cap structures facilitate RNA export from the nucleus

1990 • 411 citations

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

1991 • 391 citations

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription.

1991 • 388 citations

GLYCOSYLATION IN THE NUCLEUS AND CYTOPLASM

1989 • 380 citations

The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen.

1991 • 351 citations

The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal

1990 • 309 citations

Nucleocytoplasmic shuttling of the progesterone receptor.

1991 • 296 citations

Facilitated nuclear transport of histone H1 and other small nucleophilic proteins

1990 • 278 citations

A complex of nuclear pore proteins required for pore function.

1991 • 231 citations

Reconstitution of biochemically altered nuclear pores: Transport can be eliminated and restored

1990 • 228 citations

Mature mRNA 3′ end formation stimulates RNA export from the nucleus.

1991 • 222 citations

The NUP1 gene encodes an essential component of the yeast nuclear pore complex

1990 • 219 citations

Protein import through the nuclear pore complex is a multistep process.

1989 • 208 citations

p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins.

1991 • 203 citations

NSP1: A yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain

1990 • 180 citations

The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs.

1991 • 173 citations

A nuclear localization signal binding protein in the nucleolus.

1990 • 160 citations

Visualization of transport-related configurations of the nuclear pore transporter

1990 • 156 citations

Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport.

1991 • 144 citations

Preservation of specific RNA distribution within the chromatin-depleted nuclear substructure demonstrated by in situ hybridization coupled with biochemical fractionation.

1991 • 139 citations

When worlds collide: Immunosuppressants meet protein phosphatases

1991 • 114 citations

The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators

1991 • 106 citations

Multiple pathways in nuclear transport: the import of U2 snRNP occurs by a novel kinetic pathway.

1991 • 105 citations

Nuclear targeting of the transcription factor PTF1 is mediated by a protein subunit that does not bind to the PTF1 cognate sequence

1991 • 82 citations

Localization of a myosin heavy chain-like polypeptide to Drosophila nuclear pore complexes.

1991 • 58 citations

A yeast protein that binds nuclear localization signals: purification localization, and antibody inhibition of binding activity.

1991 • 53 citations

Human major HSP70 protein complements the localization and functional defects of cytoplasmic mutant SV40 T antigen in Swiss 3T3 mouse fibroblast cells.

1991 • 43 citations

Regulation of the extent of splicing of influenza virus NS1 mRNA: role of the rates of splicing and of the nucleocytoplasmic transport of NS1 mRNA.

1991 • 43 citations

Probing the structure and function of the nuclear pore complex.

1991 • 21 citations

Exon recognition and nucleocytoplasmic partitioning determine AMPD1 alternative transcript production.

1991 • 18 citations