Adaptive Support Ventilation Prevents Ventilator-induced Diaphragmatic Dysfunction in Piglet

Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial

2008 • 1,894 citations

Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans

2008 • 1,387 citations

Mechanics of Breathing in Man

1950 • 867 citations

Impact of systematic evaluation of pain and agitation in an intensive care unit*

2006 • 494 citations

Oxidative stress and disuse muscle atrophy

2007 • 461 citations

Mechanisms of disuse muscle atrophy: role of oxidative stress

2005 • 354 citations

Altered diaphragm contractile properties with controlled mechanical ventilation

2002 • 290 citations

Assist–Control Mechanical Ventilation Attenuates Ventilator-induced Diaphragmatic Dysfunction

2004 • 290 citations

Overestimation of Bispectral Index in Sedated Intensive Care Unit Patients Revealed by Administration of Muscle Relaxant

2003 • 286 citations

Effects of mechanical ventilation on diaphragmatic contractile properties in rats.

1994 • 284 citations

Trolox Attenuates Mechanical Ventilation–induced Diaphragmatic Dysfunction and Proteolysis

2004 • 203 citations

Effects of prolonged controlled mechanical ventilation on diaphragmatic function in healthy adult baboons

1997 • 195 citations

Caspase-3 Regulation of Diaphragm Myonuclear Domain during Mechanical Ventilation–induced Atrophy

2006 • 180 citations

Intermittent spontaneous breathing protects the rat diaphragm from mechanical ventilation effects*

2005 • 141 citations

Pressure support ventilation attenuates ventilator-induced protein modifications in the diaphragm

2008 • 139 citations

Adaptive Support Ventilation for Fast Tracheal Extubation after Cardiac Surgery

2001 • 135 citations

Mechanical Ventilation Protects against Diaphragm Injury in Sepsis

2002 • 129 citations

Automatic “Respirator/Weaning” with Adaptive Support Ventilation: The Effect on Duration of Endotracheal Intubation and Patient Management

2003 • 113 citations

Leupeptin Inhibits Ventilator-induced Diaphragm Dysfunction in Rats

2007 • 110 citations

Effects of controlled mechanical ventilation on respiratory muscle contractile properties in rabbits

2003 • 106 citations

Automatic selection of breathing pattern using adaptive support ventilation

2007 • 102 citations

Rocuronium exacerbates mechanical ventilation–induced diaphragm dysfunction in rats

2006 • 98 citations

Caspase and calpain activation both contribute to sepsis-induced diaphragmatic weakness

2009 • 89 citations

Mechanical ventilation promotes redox status alterations in the diaphragm

2006 • 89 citations

Ventilator-induced diaphragm dysfunction: the clinical relevance of animal models

2007 • 85 citations

Effects of prolonged mechanical ventilation on respiratory muscle ultrastructure and mitochondrial respiration in rabbits

2003 • 84 citations

Redox regulation of diaphragm proteolysis during mechanical ventilation

2008 • 73 citations

Adaptive support ventilation

2001 • 68 citations

Weaning Automation with Adaptive Support Ventilation: A Randomized Controlled Trial in Cardiothoracic Surgery Patients

2009 • 68 citations

Endotoxin Triggers Nuclear Factor-κB–dependent Up-regulation of Multiple Proinflammatory Genes in the Diaphragm

2006 • 65 citations

Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction

2009 • 65 citations

Preferential Diaphragmatic Weakness during Sustained Pseudomonas aeruginosa Lung Infection

2003 • 63 citations

Effects of short vs. prolonged mechanical ventilation on antioxidant systems in piglet diaphragm

2005 • 59 citations

Automating the weaning process with advanced closed-loop systems

2008 • 58 citations

Intravenous glutamine decreases lung and distal organ injury in an experimental model of abdominal sepsis

2009 • 54 citations

Adaptive Support and Pressure Support Ventilation Behavior in Response to Increased Ventilatory Demand

2009 • 43 citations

Changes in diaphragm structure following prolonged mechanical ventilation in piglets

2004 • 37 citations

Alteration of the Piglet Diaphragm Contractility In Vivo and Its Recovery after Acute Hypercapnia

2008 • 37 citations

Impact of IL-10 on Diaphragmatic Cytokine Expression and Contractility duringPseudomonasInfection

2006 • 31 citations

Determinants of Tidal Volumes with Adaptive Support Ventilation: A Multicenter Observational Study

2008 • 23 citations

Activation of the ubiquitin proteolytic pathway in human septic heart and diaphragm

2009 • 17 citations