Rocuronium exacerbates mechanical ventilation–induced diaphragm dysfunction in rats

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2004 • 1,836 citations

A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation

1995 • 1,439 citations

Phosphorylation of p70^S6kcorrelates with increased skeletal muscle mass following resistance exercise

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Clinical Practice Guidelines for Sustained Neuromuscular Blockade in the Adult Critically Ill Patient

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Mechanical Ventilation–induced Diaphragmatic Atrophy Is Associated with Oxidative Injury and Increased Proteolytic Activity

2002 • 338 citations

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Mechanical ventilation results in progressive contractile dysfunction in the diaphragm

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Assist–Control Mechanical Ventilation Attenuates Ventilator-induced Diaphragmatic Dysfunction

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Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient

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1996 • 257 citations

Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: Mechanisms at the cellular and molecular levels

2000 • 255 citations

Use of Sedatives and Neuromuscular Blockers in a Cohort of Patients Receiving Mechanical Ventilation

2005 • 205 citations

Trolox Attenuates Mechanical Ventilation–induced Diaphragmatic Dysfunction and Proteolysis

2004 • 203 citations

Effects of prolonged controlled mechanical ventilation on diaphragmatic function in healthy adult baboons

1997 • 195 citations

Mechanical ventilation-induced oxidative stress in the diaphragm

2003 • 186 citations

Proinflammatory cytokines and skeletal muscle

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Physiologic Determinants of Ventilator Dependence in Long-term Mechanically Ventilated Patients

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Myopathy Following Mechanical Ventilation for Acute Severe Asthma

1999 • 164 citations

Role of the Insulin-Like Growth Factor I Decline in the Induction of Atrogin-1/MAFbx during Fasting and Diabetes

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Muscle fibre atrophy in critically ill patients is associated with the loss of myosin filaments and the presence of lysosomal enzymes and ubiquitin

1998 • 145 citations

Effects of prolonged mechanical ventilation and inactivity on piglet diaphragm function

2002 • 133 citations

Constitutive activation of MAPK cascade in acute quadriplegic myopathy

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Mechanical ventilation induces alterations of the ubiquitin-proteasome pathway in the diaphragm

2004 • 119 citations

Detrimental effects of short-term mechanical ventilation on diaphragm function and IGF-I mRNA in rats

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Acute Treatment with Corticosteroids Decreases IGF-1 and IGF-2 Expression in the Rat Diaphragm and Gastrocnemius

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Acute type II myofiber atrophy in critical illness

1996 • 92 citations

Quadriplegic areflexic ICU illness: Selective thick filament loss and normal nerve histology

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Maximum relaxation rate of the diaphragm during weaning from mechanical ventilation.

1994 • 78 citations

Essentials of Mechanical Ventilation

1996 • 76 citations

Triamcinolone and prednisolone affect contractile properties and histopathology of rat diaphragm differently.

1993 • 75 citations

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Early effects of mechanical ventilation on isotonic contractile properties and MAF-box gene expression in the diaphragm

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Rapid changes in plasma concentrations of insulin-like growth factor-I (IGF-I), IGF-II and IGF-binding proteins during anaesthesia in young sheep

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