Activation of the ubiquitin proteolytic pathway in human septic heart and diaphragm

One-Year Outcomes in Survivors of the Acute Respiratory Distress Syndrome

2003 • 2,141 citations

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

1992 • 1,635 citations

Pathogenetic Mechanisms of Septic Shock

1993 • 1,577 citations

Profound but Reversible Myocardial Depression in Patients with Septic Shock

1984 • 1,518 citations

Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum.

1996 • 770 citations

Nitric Oxide and Cardiac Function

1996 • 721 citations

Mechanical Ventilation–induced Diaphragmatic Atrophy Is Associated with Oxidative Injury and Increased Proteolytic Activity

2002 • 338 citations

Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle.

1997 • 264 citations

Energy-ubiquitin-dependent muscle proteolysis during sepsis in rats is regulated by glucocorticoids.

1996 • 249 citations

Respiratory muscle fatigue: a cause of ventilatory failure in septic shock

1985 • 184 citations

Corticosterone Regulates Heme Oxygenase‐2 and NO Synthase Transcription and Protein Expression In Rat Brain

1994 • 148 citations

Septic shock: a heart story since the 1960s

2006 • 122 citations

Free Radical–Induced Contractile Protein Dysfunction in Endotoxin-Induced Sepsis

2001 • 115 citations

Muscular Contractile Failure in Septic Patients

2000 • 110 citations

MYOCARDIAL STRUCTURAL CHANGES IN LONG-TERM HUMAN SEVERE SEPSIS/SEPTIC SHOCK MAY BE RESPONSIBLE FOR CARDIAC DYSFUNCTION

2006 • 109 citations

Cardiac contractile impairment associated with increased phosphorylation of troponin I in endotoxemic rats

2000 • 101 citations

Peroxynitrite decomposition catalysts prevent myocardial dysfunction and inflammation in endotoxemic rats

2004 • 99 citations

Expression of Inducible Nitric Oxide Synthase in Failing and Non-failing Human Heart

1996 • 99 citations

The Bitter End

2007 • 94 citations

Peroxynitrite induces contractile dysfunction and lipid peroxidation in the diaphragm

1999 • 85 citations

Protein Tyrosine Nitration in the Ventilatory Muscles

2002 • 62 citations

Inducible nitric oxide synthase (NOS2) expressed in septic patients is nitrated on selected tyrosine residues: implications for enzymic activity

2002 • 57 citations

Human Septic Myopathy: Induction of Cyclooxygenase, Heme Oxygenase and Activation of the Ubiquitin Proteolytic Pathway

2004 • 52 citations

Effects of endotoxic shock on diaphragmatic function in mechanically ventilated rats

1992 • 50 citations

Activation of Cardiac Endothelium as a Compensatory Component in Endotoxin-Induced Cardiomyopathy

2001 • 48 citations

Paracrine regulation of cardiac myocytes in normal and septic heart

1998 • 13 citations