Identification, purification and characterization of a novel phosphatidylinositol‐specific phospholipase C, a third member of the β subfamily

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polycrylamide to nitrocellulose

1984 • 2,553 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Molecular cloning of a cDNA encoding human antihaemophilic factor

1984 • 937 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

1991 • 774 citations

Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

1990 • 650 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Src homology region 2 domains direct protein-protein interactions in signal transduction.

1990 • 498 citations

"Nonrandom" DNA sequence analysis in bacteriophage M13 by the dideoxy chain-termination method.

1982 • 279 citations

Characterization of G-protein alpha subunits in the Gq class: expression in murine tissues and in stromal and hematopoietic cell lines.

1991 • 278 citations

Inositol phospholipid-specific phospholipase C: complete cDNA and protein sequences and sequence homology to tyrosine kinase-related oncogene products.

1988 • 223 citations

The PtdIns-PLC superfamily and signal transduction

1991 • 190 citations

Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

1992 • 176 citations

Determination of the primary structure of PLC-154 demonstrates diversity of phosphoinositide-specific phospholipase C activities

1988 • 155 citations

Purification of phosphoinositide‐specific phospholipase C from a particulate fraction of bovine brain

1987 • 124 citations

Phospholipase C-148: Chromosomal Location and Deletion Mapping of Functional Domains

1988 • 81 citations

Complete cDNA encoding a putative phospholipase C from transformed human lymphocytes

1988 • 64 citations

Phospholipase C Isozymes: Structural and Functional Similarities

2007 • 57 citations

A second gene product of the inositol‐phospholipid‐specific phospholipase Cδ subclass

1991 • 46 citations