N4WBP5, a Potential Target for Ubiquitination by the Nedd4 Family of Proteins, Is a Novel Golgi-associated Protein

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Efficient selection for high-expression transfectants with a novel eukaryotic vector

1991 • 5,120 citations

UBIQUITIN-DEPENDENT PROTEIN DEGRADATION

1996 • 1,680 citations

Themes and variations on ubiquitylation

2001 • 1,475 citations

Protein ubiquitination involving an E1–E2–E3 enzyme ubiquitin thioester cascade

1995 • 960 citations

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1992 • 846 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

1997 • 696 citations

Function of WW Domains as Phosphoserine- or Phosphothreonine-Binding Modules

1999 • 663 citations

Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing

2000 • 561 citations

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

1992 • 537 citations

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide

1996 • 426 citations

The Vesicle Docking Protein p115 Binds GM130, a cis-Golgi Matrix Protein, in a Mitotically Regulated Manner

1997 • 408 citations

Ggas

2000 • 399 citations

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome

1999 • 358 citations

Ubiquitination and Endocytosis of Plasma Membrane Proteins: Role of Nedd4/Rsp5p Family of Ubiquitin-Protein Ligases

2000 • 356 citations

NeW Wrinkles for an Old Domain

2000 • 349 citations

A New Ticket for Entry into Budding Vesicles—Ubiquitin

2001 • 321 citations

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na⁺channel

2001 • 290 citations

Starvation Induces Vacuolar Targeting and Degradation of the Tryptophan Permease in Yeast

1999 • 289 citations

Components of a Ubiquitin Ligase Complex Specify Polyubiquitination and Intracellular Trafficking of the General Amino Acid Permease

2001 • 270 citations

Ubiquitin Is Required for Sorting to the Vacuole of the Yeast General Amino Acid Permease, Gap1

2001 • 231 citations

Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions

1999 • 199 citations

Yeast RSP5 and Its Human Homolog hRPF1 Potentiate Hormone-Dependent Activation of Transcription by Human Progesterone and Glucocorticoid Receptors

1996 • 160 citations

The Nedd4-like Protein KIAA0439 Is a Potential Regulator of the Epithelial Sodium Channel

2001 • 154 citations

Apical Membrane Targeting of Nedd4 Is Mediated by an Association of Its C2 Domain with Annexin Xiiib

2000 • 147 citations

cDNA Cloning, Expression Analysis, and Mapping of the MouseNedd4Gene

1997 • 142 citations

Nedd4 mediates control of an epithelial Na ⁺ channel in salivary duct cells by cytosolic Na ⁺

1998 • 140 citations

Identification and Characterization of a Novel Golgi Protein, GCP60, That Interacts with the Integral Membrane Protein Giantin

2001 • 123 citations

All Three WW Domains of Murine Nedd4 Are Involved in the Regulation of Epithelial Sodium Channels by Intracellular Na+

1999 • 123 citations

The WW module competes with the SH3 domain?

1996 • 112 citations

Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling

2001 • 106 citations

Bul1, a New Protein That Binds to the Rsp5 Ubiquitin Ligase in Saccharomyces cerevisiae

1996 • 106 citations

Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4

2000 • 106 citations

mGrb10 Interacts with Nedd4

1999 • 105 citations

A Novel Pro-Arg Motif Recognized by WW Domains

2000 • 92 citations

Organization of the Golgi apparatus

2000 • 90 citations

Forskolin inhibits and reverses the effects of brefeldin A on Golgi morphology by a cAMP-independent mechanism.

1991 • 87 citations

Anti-apoptotic Signaling of the Insulin-like Growth Factor-I Receptor through Mitochondrial Translocation of c-Raf and Nedd4

2001 • 83 citations

MDP1, a Saccharomyces cerevisiae Gene Involved in Mitochondrial/Cytoplasmic Protein Distribution, Is Identical to the Ubiquitin-Protein Ligase Gene RSP5

1997 • 70 citations

Caspase-mediated Cleavage of the Ubiquitin-protein Ligase Nedd4 during Apoptosis

1998 • 68 citations

Nuclear Import/Export of hRPF1/Nedd4 Regulates the Ubiquitin- dependent Degradation of Its Nuclear Substrates

2001 • 51 citations

Selective Inhibition of Adaptor Complex‐Mediated Vesiculation

2000 • 22 citations