Prolonged Allogeneic Islet Graft Survival by Protoporphyrins

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

2000 • 5,125 citations

Regulatory T cells in transplantation tolerance

2003 • 1,323 citations

Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice

2002 • 1,002 citations

Heme oxygenase: A novel target for the modulation of inflammatory response

1996 • 784 citations

Expression of heme oxygenase-1 can determine cardiac xenograft survival

1998 • 621 citations

Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts.

1994 • 520 citations

Upregulation of heme oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury

1999 • 489 citations

Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants

2001 • 455 citations

Cardiac-Specific Expression of Heme Oxygenase-1 Protects Against Ischemia and Reperfusion Injury in Transgenic Mice

2001 • 423 citations

Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction

2000 • 393 citations

Clinical islet transplantation: advances and immunological challenges

2004 • 360 citations

Renal Response to Tissue Injury

2000 • 274 citations

Heme Oxygenase-1 Induction in Islet Cells Results in Protection From Apoptosis and Improved In Vivo Function After Transplantation

2001 • 263 citations

The “injury response”: A concept linking nonspecific injury, acute rejection, and long-term transplant outcomes

1997 • 224 citations

HEME OXYGENASE-1 OVEREXPRESSION PROTECTS RAT HEARTS FROM COLD ISCHEMIA/REPERFUSION INJURY VIA AN ANTIAPOPTOTIC PATHWAY1

2002 • 158 citations

Long-Term Function (6 Years) of Islet Allografts in Type 1 Diabetes

1997 • 147 citations

Transfer of Heme Oxygenase 1 cDNA by a Replication-Deficient Adenovirus Enhances Interleukin 10 Production from Alveolar Macrophages That Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice

2001 • 133 citations

Heme Oxygenase 1 Gene Transfer Prevents CD95/Fas Ligand-Mediated Apoptosis and Improves Liver Allograft Survival via Carbon Monoxide Signaling Pathway

2002 • 128 citations

Gene Transfer of Heme Oxygenase-1 and Carbon Monoxide Delivery Inhibit Chronic Rejection

2002 • 126 citations

Stress protein-induced immunosuppression: inhibition of cellular immune effector functions following overexpression of haem oxygenase (HSP 32)

1998 • 114 citations

Prolonged Islet Graft Survival in NOD Mice by Blockade of the CD40-CD154 Pathway of T-Cell Costimulation

2001 • 97 citations

Adeno-Associated Virus-Mediated IL-10 Gene Therapy Inhibits Diabetes Recurrence in Syngeneic Islet Cell Transplantation of NOD Mice

2003 • 95 citations

Differential expressions of heme oxygenase-1 gene in CD25− and CD25+ subsets of human CD4+ T cells

2003 • 93 citations

A Protective Role for Heme Oxygenase Expression in Pancreatic Islets Exposed to Interleukin-1β**This work was supported by NIH Grant DK-25705 (to S.G.L.).

1998 • 91 citations

Factors influencing Islet of Langerhans graft function and monitoring

2001 • 90 citations

Low-temperature culture of human islets or in vivo treatment with L3T4 antibody produces a marked prolongation of islet human-to-mouse xenograft survival.

1987 • 87 citations

ALLEVIATION OF GRAFT-VERSUS-HOST DISEASE AFTER CONDITIONING WITH COBALT-PROTOPORPHYRIN, AN INDUCER OF HEME OXYGENASE-1

2000 • 43 citations

Tissue Culture Reduces la Antigen-bearing Cells in Rat Islets and Prolongs Islet Allograft Survival

1982 • 39 citations

Inhibition of Nitric Oxide Synthase Isoforms by Porphyrins

1996 • 29 citations

MODULATION OF THE MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN AND THE IMMUNOGENICITY OF ISLET ALLOGRAFTS

1989 • 25 citations

MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS AND MURINE ISLET ALLOGRAFT SURVIVAL

1991 • 23 citations

Overexpression of heme oxygenase-1 protects allogeneic thyroid grafts from rejection in naive mice

2000 • 15 citations