Microinjection of sigma ligands into cranial nerve nuclei produces vacuous chewing in rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

1996 • 880 citations

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

1991 • 859 citations

Sigma receptors: biology and function.

1990 • 799 citations

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain

1986 • 742 citations

Tardive dystonia

1982 • 605 citations

1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs.

1986 • 379 citations

Spontaneous orofacial movements induced in rodents by very long-term neuroleptic drug administration: phenomenology, pathophysiology and putative relationship to tardive dyskinesia

1990 • 242 citations

CLOZAPINE AND HALOPERIDOL IN A SINGLE‐BLIND CROSS‐OVER TRIAL: THERAPEUTIC AND BIOCHEMICAL ASPECTS IN THE TREATMENT OF SCHIZOPHRENIA

1974 • 198 citations

Autoradiographic visualization of haloperidol-sensitive sigma receptors in guinea-pig brain

1988 • 176 citations

Metabolites of haloperidol display preferential activity at σ receptors compared to dopamine D-2 receptors

1990 • 149 citations

Clozapine--a potential antipsychotic agent without extrapyramidal manifestations.

1974 • 98 citations

Drug specificity of pharmacological dystonia

1990 • 97 citations

A Neuroendocrine Study of Supersensitivity in Tardive Dyskinesia

1977 • 90 citations

A comparison of (−)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of σ2 receptors in motor function

1993 • 82 citations

The tardive dyskinesia syndrome.

1978 • 73 citations

Increase in rat striatal extracellular dopamine and vacous chewing produced by two σ receptor ligands

1993 • 65 citations

Epidemiology and pathophysiology of tardive dyskinesias.

1988 • 29 citations

Chemical and Structural Changes in the Brain in Patients with Movement Disorder

1985 • 26 citations

σ2 Site-mediated inhibition of electrically evoked guinea pig ileum longitudinal muscle/myenteric plexus contractions

1995 • 21 citations

Electromechanical characteristics of tardive dyskinesia

1991 • 19 citations

Subchronic administration of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine (BD1047) alters σ1 receptor binding

1997 • 16 citations

Purification and partial amino acid sequence of a 28 kDa cyclophilin-like component of the rat liver sigma receptor

1994 • 13 citations