Subchronic administration of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine (BD1047) alters σ1 receptor binding

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Sigma receptors: biology and function.

1990 • 799 citations

Steroid Binding at σ Receptors Suggests a Link Between Endocrine, Nervous, and Immune Systems

1988 • 531 citations

Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain.

1982 • 409 citations

Sigma opiates and certain antipsychotic drugs mutually inhibit (+)-[3H] SKF 10,047 and [3H]haloperidol binding in guinea pig brain membranes.

1984 • 348 citations

Sigma1 (σ1) receptor agonists and neurosteroids attenuate β25–35-amyloid peptide-induced amnesia in mice through a common mechanism

1998 • 280 citations

Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism

1995 • 253 citations

Novel antipsychotic drugs share high affinity for σ receptors

1988 • 206 citations

Evidence for a role of haloperidol‐sensitive σ‐'opiate' receptors in the motor effects of antipsychotic drugs

1988 • 183 citations

In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands.

1992 • 173 citations

Cytotoxic effects of sigma ligands: sigma receptor-mediated alterations in cellular morphology and viability

1995 • 164 citations

Structural determinants of sigma receptor affinity.

1987 • 124 citations

Drug specificity of pharmacological dystonia

1990 • 97 citations

A comparison of (−)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of σ2 receptors in motor function

1993 • 82 citations

Pharmacologic analysis of drug-receptor interaction (2nd edition): Edited by T Kenakin. (Pp 468; $113.50.) New York: Reven Press, 1993. ISBN 0-7817-0065-5

1995 • 80 citations

Motor effects of two sigma ligands mediated by nigrostriatal dopamine neurons

1989 • 75 citations

Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes.

1991 • 72 citations

Synthesis, characterization, and biological evaluation of a novel class of N-(arylethyl)-N-alkyl-2-(1-pyrrolidinyl)ethylamines: structural requirements and binding affinity at the .sigma. receptor

1992 • 64 citations

Regional variation in the ratio of σ1 to σ2 binding in rat brain

1994 • 62 citations

Possible cerebroprotective and in vivo NMDA antagonist activities of sigma agents

1991 • 62 citations

Receptor Cell Biology: Receptor-Mediated Endocytosis

1995 • 57 citations

Sertraline potently displaces (+)-[3H]3-PPP binding to σ sites in rat brain

1989 • 55 citations

Evaluation of U-50,488H analogs for neuroprotective activity in the gerbil

1991 • 49 citations

Psychotomimetic opioid binding: specific binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain

1981 • 43 citations

SKF 525-A and cytochrome P-450 ligands inhibit with high affinity the binding of [3H]dextromethorpan and σ ligands to guinea pig brain.

1991 • 40 citations

Heterogeneous Binding of Sigma Radioligands in the Rat Brain and Liver: Possible Relationship to Subforms of Cytochrome P‐450

1991 • 39 citations

Chronic neuroleptic treatment and dopamine receptor regulation.

1980 • 37 citations

Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo

1990 • 24 citations

Receptor-mediated endocytosis: machinery and regulation of the clathrin-coated vesicle pathway.

1983 • 22 citations

Dissociation of the motor effects of (+)-pentazocine from binding to σ1 sites

1996 • 15 citations

Characterization of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) binding sites in C57BL/6 mouse brain: mutual effects of monoamine oxidase inhibitors and sigma ligands on MPTP and sigma binding sites.

1991 • 14 citations

Possible expression of a σ1 site in rat pheochromocytoma (PC12) cells

1996 • 13 citations

Up and Down Regulation

1982 • 9 citations