Diabetes-induced activation of protein kinase C inhibits store-operated Ca 2+ uptake in rat retinal microvascular smooth muscle

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus

1993 • 23,535 citations

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

1998 • 19,638 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.

1998 • 8,603 citations

Dietary Advanced Glycation End Products and Their Potential Role in Cardiometabolic Disease in Children

2016 • 3,967 citations

Store depletion and calcium influx

1997 • 1,422 citations

Protein kinase C activation and the development of diabetic complications.

1998 • 1,328 citations

Protein kinase C signaling and oxidative stress

2000 • 691 citations

SIGNAL TRANSMISSION BETWEEN THE PLASMA MEMBRANE AND NUCLEUS OF T LYMPHOCYTES

1994 • 634 citations

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca ²⁺ -Dependent Protein Kinase

1984 • 618 citations

The Sevenfold Way of PKC Regulation

1998 • 496 citations

Characterization of the Mechanism for the Chronic Activation of Diacylglycerol-Protein Kinase C Pathway in Diabetes and Hypergalactosemia

1994 • 444 citations

Retinal Vascular Patterns

1963 • 329 citations

Pathogenesis of Diabetic Retinopathy

1989 • 325 citations

Protein kinase C and the development of diabetic vascular complications

2001 • 314 citations

Role of Blood Flow and Impaired Autoregulation in the Pathogenesis of Diabetic Retinopathy

1995 • 311 citations

Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation

1993 • 306 citations

Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation.

2000 • 268 citations

Ocular blood flow and associated functional deviations in diabetic retinopathy

1999 • 224 citations

Regulation of cardiac and smooth muscle Ca²⁺channels (Ca_V1.2a,b) by protein kinases

2001 • 214 citations

Capacitative Ca 2+ Entry Exclusively Inhibits cAMP Synthesis in C6-2B Glioma Cells

1995 • 163 citations

Correlation of Fluorescein Angiogram and Retinal Digest in Diabetic Retinopathy

1970 • 152 citations

Expression of the inducible isoform of nitric oxide synthase in the retinas of human subjects with diabetes mellitus

2001 • 120 citations

A Contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit

1987 • 115 citations

Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia

1994 • 106 citations

Potential new medical therapies for diabetic retinopathy: protein kinase C inhibitors

2002 • 105 citations

Epsilon-isoenzyme of protein kinase C induces a Ca(2+)-independent contraction in vascular smooth muscle

1996 • 102 citations

Activation of store‐operated channels by noradrenaline via protein kinase C in rabbit portal vein myocytes

2002 • 98 citations

Nifedipine blocks Ca²⁺ store refilling through a pathway not involving L‐type Ca²⁺ channels in rabbit arteriolar smooth muscle

2001 • 94 citations

Clinicopathologic Correlations in Diabetic Retinopathy

1977 • 88 citations

Two distinct membrane currents activated by cyclopiazonic acid‐induced calcium store depletion in single smooth muscle cells of the mouse anococcygeus

1996 • 87 citations

Nitric Oxide Synthase Activity in Retinas from Non-Insulin-Dependent Diabetic Goto-Kakizaki Rats: Correlation with Blood–Retinal Barrier Permeability

2000 • 87 citations

Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy

1995 • 86 citations

Diabetic Glycemic Control and Retinal Blood Flow

1990 • 83 citations

Attenuated responses to endothelin‐1, KCl and CaCl₂, but not noradrenaline, of aortae from rats with streptozotocin‐induced diabetes mellitus

1991 • 82 citations

Capacitative Ca2+ entry regulates Ca2+-sensitive adenylyl cyclases

1994 • 82 citations

Pathogenesis of diabetic retinopathy

1989 • 72 citations

Functional impairment of renal afferent arteriolar voltage-gated calcium channels in rats with diabetes mellitus.

1996 • 71 citations

Constitutive nitric oxide synthase is associated with retinal vascular permeability in early diabetic rats

2001 • 70 citations

Selective loss of vascular smooth muscle cells in the retinal microcirculation of diabetic dogs.

1994 • 67 citations

High glucose level inhibits capacitative Ca 2 + influx in cultured rat mesangial cells by a protein kinase C-dependent mechanism

1997 • 53 citations

Protein Kinase C Activates Store-operated Ca2+Channels in Human Glomerular Mesangial Cells

2001 • 50 citations

Increased vasodilatory prostaglandin production in the diabetic rat retinal vasculature

1999 • 49 citations

Protein kinase Cα participates in activation of store-operated Ca²⁺channels in human glomerular mesangial cells

2002 • 46 citations

Altered L-type Ca²⁺ channel currents in vascular smooth muscle cells from experimental diabetic rats

2000 • 46 citations

Ca2+ oscillations and Ca2+ influx in Xenopus oocytes expressing a novel 5‐hydroxytryptamine receptor.

1993 • 46 citations

Heterogeneity in Cytosolic Calcium Regulation among Different Microvascular Smooth Muscle Cells of the Rat Retina

2000 • 41 citations

Signal Transmission between the Plasma Membrane and Nucleus of T Lymphocytes

1994 • 41 citations

The unimportance of being (protein kinase C) epsilon¹

1998 • 35 citations

Reversal of abnormal retinal hemodynamics in diabetic rats by acarbose, an α-glucosidase inhibitor

1995 • 30 citations

Diabetic glycemic control and retinal blood flow

1990 • 26 citations

Effect of Glucose on Endothelin-1-induced Calcium Transients in Cultured Bovine Retinal Pericytes

1999 • 26 citations

Hyperglycemia alters cytoplasmic Ca2+ responses to capacitative Ca2+ influx in rat aortic smooth muscle cells

1995 • 25 citations

The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle

2000 • 23 citations

Hyperosmolality-induced abnormal patterns of calcium mobilization in smooth muscle cells from non-diabetic and diabetic rats.

1998 • 19 citations

Induction Of Endothelin‐1 Expression By Glucose: An Effect Of Protein Kinase C Activation

2001 • 19 citations

Caffeine stimulates Ca²⁺ entry through store‐operated channels to activate tyrosine hydroxylase in bovine chromaffin cells

2002 • 14 citations

The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle

2000 • 8 citations

Diminishment of Contractions Associated with Depolarization-Evoked Activation of Ca<sup>2+</sup> Channels in Diabetic Rat Aorta

1996 • 6 citations