Capacitative Ca 2+ Entry Exclusively Inhibits cAMP Synthesis in C6-2B Glioma Cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Capacitative calcium entry revisited

1990 • 1,499 citations

Range of Messenger Action of Calcium Ion and Inositol 1,4,5-Trisphosphate

1992 • 1,144 citations

Regulation in metabolism

1973 • 780 citations

Regulation in Metabolism

1974 • 607 citations

Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

1989 • 583 citations

Characterization of ionomycin as a calcium ionophore.

1978 • 535 citations

Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release

1993 • 448 citations

Overview: Purinergic Mechanisms

1990 • 408 citations

Adenylyl cyclases

1992 • 397 citations

Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane

1994 • 305 citations

Molecular and functional diversity of mammalian G _s ‐stimulated adenylyl cyclases

1993 • 295 citations

Isolation and characterization of a novel cardiac adenylylcyclase cDNA.

1992 • 263 citations

Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.

1992 • 262 citations

Cloning and characterization of a sixth adenylyl cyclase isoform: types V and VI constitute a subgroup within the mammalian adenylyl cyclase family.

1992 • 201 citations

Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases.

1992 • 175 citations

cAMP-dependent protein kinase and lipolysis in rat adipocytes. II. Definition of steady-state relationship with lipolytic and antilipolytic modulators.

1985 • 168 citations

Molecular diversity in the adenylylcyclase family. Evidence for eight forms of the enzyme and cloning of type VI.

1992 • 159 citations

Y₁ receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase

1990 • 136 citations

Localized Ca2+ entry preferentially effects protein dephosphorylation, phosphorylation, and glutamate release.

1992 • 136 citations

Muscarinic cholinergic receptor-mediated activation of phosphodiesterase.

1982 • 133 citations

Agonist-induced localized Ca2+ spikes directly triggering exocytotic secretion in exocrine pancreas.

1993 • 115 citations

Calcium Is an Inhibitor of Luteinizing Hormone-Sensitive Adenylate Cyclase in the Luteal Cell*

1984 • 96 citations

Selective expression of one Ca2+-inhibitable adenylyl cyclase in dopaminergically innervated rat brain regions

1994 • 94 citations

Bradykinin stimulates Ca2+ mobilization in NCB-20 cells leading to direct inhibition of adenylylcyclase. A novel mechanism for inhibition of cAMP production.

1991 • 94 citations

Muscarinic cholinergic receptors of two cell lines that regulate cyclic AMP metabolism by different molecular mechanisms.

1984 • 91 citations

Calcium entry via L-type calcium channels acts as a negative regulator of adenylyl cyclase activity and cyclic AMP levels in cardiac myocytes.

1993 • 85 citations

Capacitative Ca2+ entry regulates Ca2+-sensitive adenylyl cyclases

1994 • 82 citations

Ionomycin acts as an ionophore to release TRH-regulated Ca2+ stores from GH4C1 cells

1986 • 64 citations

Dual coupling of cloned human 5-hydroxytryptamine1D alpha and 5-hydroxytryptamine1D beta receptors stably expressed in murine fibroblasts: inhibition of adenylate cyclase and elevation of intracellular calcium concentrations via pertussis toxin-sensitive G protein(s).

1993 • 63 citations

Calcium inhibition of cardiac adenylyl cyclase. Evidence for two distinct sites of inhibition

1991 • 60 citations

Molecular cloning and expression of a novel type V adenylyl cyclase from rabbit myocardium

1994 • 50 citations

ADP and, indirectly, ATP are potent inhibitors of cAMP production in intact isoproterenol-stimulated C6 glioma cells

1989 • 50 citations

A mechanism in the control of intracellular cAMP level: the activation of a calmodulin-sensitive phosphodiesterase by a rise of intracellular free calcium

1985 • 48 citations

Inhibition of cAMP accumulation by intracellular calcium mobilization in C6-2B cells stably transfected with substance K receptor cDNA.

1991 • 47 citations

Predominant expression of type-VI adenylate cyclase in C6-2B rat glioma cells may account for inhibition of cyclic AMP accumulation by calcium

1993 • 44 citations

Rapid application and removal of second messengers to cyclic nucleotide-gated channels from olfactory epithelium.

1993 • 43 citations

Ca2+-inhibited adenylyl cyclase in cardiac tissue

1993 • 43 citations

P2U-purinergic receptors on C6-2B rat glioma cells: modulation of cytosolic Ca2+ and cAMP levels by protein kinase C.

1993 • 39 citations

Pharmacological characterization of endothelin-stimulated phosphoinositide breakdown and cytosolic free Ca2+ rise in rat C6 glioma cells

1992 • 38 citations

Endothelin- and ATP-induced inhibition of adenylyl cyclase activity in C6 glioma cells: role of Gi and calcium.

1993 • 27 citations

Ca+2 Is an Inhibitor of Adenylate Cyclase in MA-10 Leydig Tumor Cells*

1988 • 27 citations

Transfected Go1 alpha inhibits the calcium dependence of beta-adrenergic stimulated cAMP accumulation in C6 glioma cells.

1993 • 24 citations

Ca2+ inhibition of beta-adrenergic receptor- and forskolin-stimulated cAMP accumulation in C6-2B rat glioma cells is independent of protein kinase C.

1993 • 21 citations

Inhibition of Cyclic AMP Accumulation in Intact NCB‐20 Cells as a Direct Result of Elevation of Cytosolic Ca²⁺

1992 • 19 citations

Manipulation of Intracellular Calcium in NCB‐20 Cells

1992 • 16 citations

Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase

1993 • 15 citations