The involvement of protein kinase C in myosin phosphorylation and force development in rat tail arterial smooth muscle

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Cyanobacterial microcystin‐LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants

1990 • 1,627 citations

Signal transduction by G‐proteins, Rho‐kinase and protein phosphatase to smooth muscle and non‐muscle myosin II

2000 • 1,219 citations

Chelerythrine is a potent and specific inhibitor of protein kinase C

1990 • 1,208 citations

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

1989 • 1,126 citations

Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin.

1994 • 923 citations

Rho-associated Kinase Directly Induces Smooth Muscle Contraction through Myosin Light Chain Phosphorylation

1997 • 576 citations

Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase.

1987 • 503 citations

Cross-bridge phosphorylation and regulation of latch state in smooth muscle

1988 • 437 citations

Wortmannin, a microbial product inhibitor of myosin light chain kinase.

1992 • 434 citations

Smooth muscle calponin. Inhibition of actomyosin MgATPase and regulation by phosphorylation.

1990 • 410 citations

Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase.

1985 • 340 citations

Agonists Trigger G Protein-mediated Activation of the CPI-17 Inhibitor Phosphoprotein of Myosin Light Chain Phosphatase to Enhance Vascular Smooth Muscle Contractility

2000 • 336 citations

A Novel Protein Phosphatase-1 Inhibitory Protein Potentiated by Protein Kinase C. Isolation from Porcine Aorta Media and Characterization1

1995 • 302 citations

Molecular cloning of a novel phosphorylation‐dependent inhibitory protein of protein phosphatase‐1 (CPI17) in smooth muscle: its specific localization in smooth muscle¹

1997 • 247 citations

Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin.

1986 • 246 citations

Phosphorylation of the 20,000-dalton light chain of smooth muscle myosin by the calcium-activated, phospholipid-dependent protein kinase. Phosphorylation sites and effects of phosphorylation.

1987 • 224 citations

Phosphorylation of CPI‐17, an inhibitory phosphoprotein of smooth muscle myosin phosphatase, by Rho‐kinase

2000 • 220 citations

Ca2+-dependent hydrophobic-interaction chromatography. Isolation of a novel Ca2+-binding protein and protein kinase C from bovine brain

1984 • 202 citations

Phosphorylation of the Large Subunit of Myosin Phosphatase and Inhibition of Phosphatase Activity

1996 • 197 citations

The biochemical basis of the regulation of smooth-muscle contraction

1994 • 187 citations

Inhibition of Rho‐associated kinase blocks agonist‐induced Ca²⁺ sensitization of myosin phosphorylation and force in guinea‐pig ileum

2000 • 186 citations

A novel mechanism for the Ca(2+)-sensitizing effect of protein kinase C on vascular smooth muscle: inhibition of myosin light chain phosphatase.

1994 • 182 citations

Possible involvement of the novel CPI‐17 protein in protein kinase C signal transduction of rabbit arterial smooth muscle

1998 • 172 citations

Reconstitution of protein kinase C‐induced contractile Ca²⁺ sensitization in Triton X‐100‐demembranated rabbit arterial smooth muscle

1999 • 153 citations

Enhanced Myosin Light Chain Phosphorylations as a Central Mechanism for Coronary Artery Spasm in a Swine Model With Interleukin-1β

1997 • 153 citations

Ca²⁺‐independent phosphorylation of myosin in rat caudal artery and chicken gizzard myofilaments

1999 • 140 citations

GTP gamma S-dependent regulation of smooth muscle contractile elements

1992 • 139 citations

Effect of Multiple Phosphorylations of Smooth Muscle and Cytoplasmic Myosins on Movement in an in Vitro Motility Assay

1989 • 137 citations

Sites phosphorylated in myosin light chain in contracting smooth muscle.

1988 • 113 citations

A major role for the Rho‐associated coiled coil forming protein kinase in G‐protein‐mediated Ca²⁺ sensitization through inhibition of myosin phosphatase in rabbit trachea

1999 • 109 citations

Possible role of atypical protein kinase C activated by arachidonic acid in Ca2+ sensitization of rabbit smooth muscle.

1997 • 102 citations

Phosphorylation of smooth muscle myosin heavy and light chains

1989 • 98 citations

Dynamics of myosin light chain phosphorylation at Ser¹⁹ and Thr¹⁸/Ser¹⁹in smooth muscle cells in culture

1998 • 87 citations

Effects of calcium and substrate on force‐velocity relation and energy turnover in skinned smooth muscle of the guinea‐pig.

1985 • 84 citations

Mechanisms of Ca²⁺ sensitization of force production by noradrenaline in rat mesenteric small arteries

1998 • 60 citations

Myosin light chain phosphorylation in 32P-labeled rabbit aorta stimulated by phorbol 12,13-dibutyrate and phenylephrine

1989 • 57 citations

The relationship between ATPase activity, isometric force, and myosin light-chain phosphorylation and thiophosphorylation in skinned smooth muscle fiber bundles from chicken gizzard.

1990 • 52 citations

Inhibition of myosin light chain phosphatase during Ca(2+)-independent vasocontraction

1993 • 50 citations

Amino acid sequence of chicken gizzard smooth muscle SM22 alpha.

1987 • 50 citations

Urea‐glycerol‐acrylamide gel electrophoresis of acidic low molecular weight muscle proteins: Rapid determination of myosin light chain phosphorylation in myosin, actomyosin and whole muscle samples

1986 • 47 citations

Effects of calyculin A on tension and myosin phosphorylation in skinned smooth muscle of the rabbit mesenteric artery

1993 • 45 citations

Stimulus-specific patterns of myosin light chain phosphorylation in smooth muscle of rabbit thoracic artery

1990 • 41 citations

Phosphorylation of two sites on smooth muscle myosin. Effects on contraction of glycerinated vascular smooth muscle.

1988 • 40 citations

α1-Adrenoceptor-mediated phosphorylation of myosin in rat-tail arterial smooth muscle

1997 • 34 citations

Intimal Hyperplasia Enhances Myosin Phosphorylation in Rabbit Carotid Artery

1993 • 29 citations

Long-term regulation of contractility and calcium current in smooth muscle

1997 • 27 citations

Phosphatase inhibition with okadaic acid does not alter the relationship between force and myosin light chain phosphorylation in permeabilized smooth muscle

1989 • 27 citations

Activation of smooth muscle myosin Mg2+-ATPase by native thin filaments and actin/tropomyosin.

1987 • 26 citations

The variable coupling between force and myosin light chain phosphorylation in Triton-skinned chicken gizzard fibre bundles: role of myosin light chain phosphatase

1995 • 22 citations

The role of myosin light chain kinase-dependent phosphorylation of myosin light chain in phorbol ester-induced contraction of rabbit aorta

1997 • 17 citations