In vivo and in vitro phosphorylation of the human estrogen receptor

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

1991 • 501 citations

Phosphorylation of the human estrogen receptor. Identification of hormone-regulated sites and examination of their influence on transcriptional activity.

1994 • 460 citations

Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region.

1993 • 451 citations

Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

1992 • 387 citations

Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

1990 • 355 citations

Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain

1993 • 345 citations

Oncoprotein-mediated signalling cascade stimulates c-Jun activity by phosphorylation of serines 63 and 73.

1992 • 343 citations

FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains

1992 • 333 citations

In vivo protein–DNA interactions in a glucocorticoid response element require the presence of the hormone

1986 • 328 citations

Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element.

1993 • 322 citations

Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.

1991 • 304 citations

A DNA-activated protein kinase from HeLa cell nuclei.

1990 • 285 citations

Cyclic AMP-dependent protein kinase phosphorylates and inactivates the yeast transcriptional activator ADR1

1989 • 247 citations

Phosphorylation of Steroid Hormone Receptors*

1992 • 243 citations

Human vitamin D receptor is selectively phosphorylated by protein kinase C on serine 51, a residue crucial to its trans-activation function.

1991 • 233 citations

Identification of an estrogen-responsive element from the 5'-flanking region of the rat prolactin gene.

1987 • 231 citations

Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein

1993 • 220 citations

Synergistic activation of estrogen receptor-mediated transcription by estradiol and protein kinase activators.

1993 • 197 citations

Several regions of human estrogen receptor are involved in the formation of receptor-heat shock protein 90 complexes

1990 • 189 citations

Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor.

1994 • 165 citations

Estrogen Receptor Synthesis and Turnover in MCF-7 Breast Cancer Cells Measured by a Density Shift Technique*

1984 • 142 citations

The nuclear-bound form of the progesterone receptor is generated through a hormone-dependent phosphorylation

1985 • 132 citations

Estrogen receptor phosphorylation. Hormonal dependence and consequence on specific DNA binding.

1992 • 132 citations

Agonist-dependent phosphorylation and nuclear dephosphorylation of glucocorticoid receptors in intact cells

1989 • 126 citations

Hormone- and DNA-binding mechanism of the recombinant human estrogen receptor

1993 • 119 citations

The phosphorylation and DNA binding of the DNA-binding domain of the orphan nuclear receptor NGFI-B.

1993 • 115 citations

Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site

1993 • 115 citations

Expression and complex formation of simian virus 40 large T antigen and mouse p53 in insect cells

1988 • 107 citations

Characterization and Functional Properties of the A and B Forms of Human Progesterone Receptors Synthesized in a Baculovirus System

1991 • 105 citations

Properties of a purified estradiol-dependent calf uterus tyrosine kinase

1993 • 89 citations

Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor

1994 • 84 citations

Oncoprotein-Mediated Signalling Cascade Stimulates c-Jun Activity by Phosphorylation of Serines 63 and 73

1992 • 83 citations

Phosphorylation stimulates the transcriptional activity of the human beta 1 thyroid hormone nuclear receptor.

1992 • 76 citations

Multiple signaling pathways activate the chicken progesterone receptor.

1994 • 75 citations

Modulation of the estrogen receptor's affinity for DNA by estradiol.

1985 • 73 citations

Kinetics of glucocorticoid receptor phosphorylation in intact cells. Evidence for hormone-induced hyperphosphorylation after activation and recycling of hyperphosphorylated receptors.

1993 • 71 citations

Characterization of ligand-dependent phosphorylation of the estrogen receptor.

1994 • 65 citations

Phosphorylation of steroid hormone receptors

1992 • 65 citations

Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays.

1992 • 60 citations

Identification of an Estrogen-Responsive Element from the 5′-Flanking Region of the Rat Prolactin Gene

1987 • 59 citations

Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system

1991 • 58 citations

Hormone-Dependent Regulation of Chicken Progesterone Receptor Deoxyribonucleic Acid Binding and Phosphorylation*

1989 • 49 citations

Nuclear estrogen receptor molecular heterogeneity in the mouse uterus.

1988 • 46 citations

Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays

1992 • 25 citations