'New' functions for 'old' proteins: The role of the calcium-binding proteins calbindin D-28k, calretinin and parvalbumin, in cerebellar physiology. Studies with knockout mice

Calbindin D-28k and parvalbumin in the rat nervous system

1990 • 2,068 citations

Sodium/Calcium Exchange: Its Physiological Implications

1999 • 1,690 citations

Calcium-binding proteins in the nervous system

1992 • 1,321 citations

Vesicle Pools and Ca2+ Microdomains: New Tools for Understanding Their Roles in Neurotransmitter Release

1998 • 1,021 citations

The S100 family of EF-hand calcium-binding proteins: functions and pathology

1996 • 1,002 citations

Structure And Evolution Of Calcium-Modulated Protein

1980 • 942 citations

Dendritic spines as basic functional units of neuronal integration

1995 • 933 citations

Detection of Calcium Binding Proteins by 45Ca Autoradiography on Nitrocellulose Membrane after Sodium Dodecyl Sulfate Gel Electrophoresis1

1984 • 772 citations

Vitamin D ₃ -Induced Calcium-Binding Protein in Chick Intestinal Mucosa

1966 • 740 citations

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1

1994 • 730 citations

Dynamic organization of motor control within the olivocerebellar system

1995 • 680 citations

Cerebellum Implicated in Sensory Acquisition and Discrimination Rather Than Motor Control

1996 • 679 citations

The Cerebellum: A Neuronal Learning Machine?

1996 • 615 citations

A Miniature Head-Mounted Two-Photon Microscope

2001 • 599 citations

Correlation of physiological subgroupings of nonpyramidal cells with parvalbumin- and calbindinD28k-immunoreactive neurons in layer V of rat frontal cortex

1993 • 568 citations

Calretinin: a gene for a novel calcium-binding protein expressed principally in neurons [published erratum appears in J Cell Biol 1990 May;110(5):1845]

1987 • 561 citations

Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches

1997 • 523 citations

Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites

1998 • 521 citations

Interplay between Facilitation, Depression, and Residual Calcium at Three Presynaptic Terminals

2000 • 516 citations

Determinants of the Time Course of Facilitation at the Granule Cell to Purkinje Cell Synapse

1996 • 487 citations

Calretinin in rat brain: An immunohistochemical study

1992 • 479 citations

Coincidence detection in single dendritic spines mediated by calcium release

2000 • 475 citations

Electrical synapses between Gaba-Releasing interneurons

2001 • 431 citations

A new class of synaptic response involving calcium release in dendritic spines

1998 • 415 citations

Groupings of nonpyramidal and pyramidal cells with specific physiological and morphological characteristics in rat frontal cortex

1993 • 401 citations

Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene

1997 • 397 citations

Role of the calcium-binding protein parvalbumin in short-term synaptic plasticity

2000 • 393 citations

From form to function: calcium compartmentalization in dendritic spines

2000 • 382 citations

Transmitter release modulation by intracellular Ca²⁺ buffers in facilitating and depressing nerve terminals of pyramidal cells in layer 2/3 of the rat neocortex indicates a target cell‐specific difference in presynaptic calcium dynamics

2001 • 375 citations

Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKCγ mutant mice

1995 • 369 citations

Residual Ca2 + and short-term synaptic plasticity

1994 • 353 citations

Calcium buffering properties of calbindin D28k and parvalbumin in rat sensory neurones.

1993 • 348 citations

Classification and evolution of EF-hand proteins.

1998 • 345 citations

Usefulness and limitations of linear approximations to the understanding of Ca++ signals

1998 • 322 citations

Can calmodulin function without binding calcium?

1991 • 318 citations

Dendritic spines of rat cerebellar Purkinje cells: serial electron microscopy with reference to their biophysical characteristics

1988 • 316 citations

Electrotonic Coupling Interacts with Intrinsic Properties to Generate Synchronized Activity in Cerebellar Networks of Inhibitory Interneurons

1999 • 310 citations

Subthreshold synaptic Ca2+ signalling in fine dendrites and spines of cerebellar Purkinje neurons

1995 • 309 citations

Correlation of parvalbumin concentration with relaxation speed in mammalian muscles.

1982 • 302 citations

Modeling Buffered Ca2+ Diffusion Near the Membrane

1997 • 285 citations

Cre recombinase expression in cerebellar Purkinje cells

2000 • 284 citations

Calcium-induced calcium release in cerebellar purkinje cells

1994 • 279 citations

Two types of calcium response limited to single spines in cerebellar Purkinje cells.

1995 • 275 citations

Inositol 1,4,5-tris-phosphate activation of inositol tris-phosphate receptor Ca ²⁺ channel by ligand tuning of Ca ²⁺ inhibition

1998 • 263 citations

Ryanodine and inositol trisphosphate receptors coexist in avian cerebellar Purkinje neurons.

1991 • 258 citations

Spread of dendritic excitation in layer 2/3 pyramidal neurons in rat barrel cortex in vivo

1999 • 257 citations

Magnesium and calcium binding to parvalbumins: evidence for differences between parvalbumins and an explanation of their relaxing function

1979 • 234 citations

Relationship of neuronal vulnerability and calcium binding protein immunoreactivity in ischemia

1990 • 223 citations

Prolonged contraction-relaxation cycle of fast-twitch muscles in parvalbumin knockout mice

1999 • 209 citations

Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin

1999 • 202 citations

Immunoreactivity for calretinin and other calcium-binding proteins in cerebellum

1989 • 196 citations

Regulation of Spine Calcium Dynamics by Rapid Spine Motility

2000 • 196 citations

Release of calcium from stores alters the morphology of dendritic spines in cultured hippocampal neurons

1999 • 189 citations

The inhibitory interneurones within the cerebellar cortex

1966 • 188 citations

Single-domain/bound calcium hypothesis of transmitter release and facilitation

1996 • 187 citations

Binding Kinetics of Calbindin-D28k Determined by Flash Photolysis of Caged Ca2+

2000 • 185 citations

High endogenous calcium buffering in Purkinje cells from rat cerebellar slices.

1996 • 184 citations

Pattern of neuronal death in the rat hippocampus after status epilepticus. Relationship to calcium binding protein content and ischemic vulnerability

1992 • 175 citations

Calretinin-immunoreactive neocortical interneurons are unaffected in Alzheimer's disease

1993 • 171 citations

Kinetics of Ca²⁺ binding to parvalbumin in bovine chromaffin cells: implications for [Ca²⁺] transients of neuronal dendrites

2000 • 171 citations

Serotonin-Driven Long-Range Inhibitory Connections in the Cerebellar Cortex

2000 • 164 citations

Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.

1996 • 158 citations

On the dissociation constants of BAPTA-type calcium buffers

1989 • 145 citations

Impaired long-term potentiation induction in dentate gyrus of calretinin-deficient mice

1997 • 144 citations

Surviving Granule Cells of the Sclerotic Human Hippocampus Have Reduced Ca²⁺Influx Because of a Loss of Calbindin-D_28kin Temporal Lobe Epilepsy

2000 • 143 citations

Intracellular calcium clearance in Purkinje cell somata from rat cerebellar slices

1998 • 142 citations

Two types of ryanodine receptors in mouse brain: Skeletal muscle type exclusively in Purkinje cells and cardiac muscle type in various neurons

1992 • 141 citations

The unipolar brush cells of the rat cerebellar cortex and cochlear nucleus are calretinin-positive: a study by light and electron microscopic immunocytochemistry

1994 • 140 citations

Calretinin modifies presynaptic calcium signaling in frog saccular hair cells

2000 • 139 citations

Guidebook to the calcium binding proteins

1998 • 136 citations

Supralinear Ca2+ Signaling by Cooperative and Mobile Ca2+ Buffering in Purkinje Neurons

1999 • 135 citations

Distribution of unipolar brush cells and other calretinin immunoreactive components in the mammalian cerebellar cortex.

1999 • 131 citations

Differences in Ca²⁺ buffering properties between excitatory and inhibitory hippocampal neurons from the rat

2000 • 130 citations

Calbindin D28K Overexpression Protects Striatal Neurons From Transient Focal Cerebral Ischemia

2001 • 122 citations

Regulation of excitatory transmission at hippocampal synapses by calbindin D28k.

1995 • 119 citations

Parvalbumin content and Ca2+ and Mg2+ dissociation rates correlated with changes in relaxation rate of frog muscle fibres.

1991 • 116 citations

Calbindin-D28k fails to protect hippocampal neurons against ischemia in spite of its cytoplasmic calcium buffering properties: evidence from calbindin-D28k knockout mice

1998 • 108 citations

Neurodegenerative and morphogenic changes in a mouse model of temporal lobe epilepsy do not depend on the expression of the calcium-binding proteins parvalbumin, calbindin, or calretinin

2000 • 107 citations

Alterations in Purkinje cell spines of calbindin D‐28 k and parvalbumin knock‐out mice

2000 • 102 citations

Ca2+ release from Ca2+ stores, particularly from ryanodine-sensitive Ca2+ stores, is required for the induction of LTD in cultured cerebellar Purkinje cells

1995 • 102 citations

Does the calcium binding protein calretinin protect dopaminergic neurons against degeneration in Parkinson's disease?

1994 • 102 citations

Calcium signaling in a narrow somatic submembrane shell during synaptic activity in cerebellar Purkinje neurons.

1995 • 100 citations

Comparison of the Ca2+-binding Properties of Human Recombinant Calretinin-22k and Calretinin

1997 • 99 citations

Axons and axon terminals of cerebellar Purkinje cells and basket cells have higher levels of parvalbumin immunoreactivity than somata and dendrites: quantitative analysis by immunogold labeling

1993 • 94 citations

Expression of calbindin-D28K in motoneuron hybrid cells after retroviral infection with calbindin-D28K cDNA prevents amyotrophic lateral sclerosis IgG-mediated cytotoxicity.

1996 • 91 citations

Vulnerability of Midbrain Dopaminergic Neurons in Calbindin‐D_28k‐deficient Mice: Lack of Evidence for a Neuroprotective Role of Endogenous Calbindin in MPTPtreated and Weaver Mice

1997 • 91 citations

Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function

1999 • 87 citations

REGIONAL NEURONE DAMAGE AFTER CEREBRAL ISCHAEMIA IN THE NORMO‐ AND HYPOGLYCAEMIC RAT

1981 • 86 citations

Geometry of Dendritic Spines Affects Calcium Dynamics in Hippocampal Neurons: Theory and Experiments

1999 • 85 citations

Deficiency in parvalbumin increases fatigue resistance in fast-twitch muscle and upregulates mitochondria

2001 • 85 citations

Calretinin and calbindin D-28k delay the onset of cell death after excitotoxic stimulation in transfected P19 cells

2001 • 84 citations

Gene knockout studies of Ca²⁺‐transporting ATPases

2000 • 83 citations

Calcium and magnesium binding to rat parvalbumin

1994 • 83 citations

Autoradiographic localization of cerebellar excitatory amino acid binding sites in the mouse

1987 • 82 citations

Distribution of Calretinin, Calbindin D28k, and Parvalbumin in Subcellular Fractions of Rat Cerebellum: Effects of Calcium

1995 • 81 citations

Competitive calcium binding: implications for dendritic calcium signaling.

1998 • 80 citations

Striatal interneurons in Huntington's disease: Selective increase in the density of calretinin‐immunoreactive medium‐sized neurons

1996 • 80 citations

Immunolocalization of the plasma membrane Ca2+ pump isoforms in the rat brain

1997 • 79 citations

Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K

1994 • 78 citations

Interaction between responses in Purkinje cells evoked by climbing fibre impulses and parallel fibre volleys in the cat.

1983 • 78 citations

Fractional calcium current through neuronal AMPA-receptor channels with a low calcium permeability

1996 • 77 citations

Calcium-binding proteins in primate cerebellum

1998 • 75 citations

Mechanism of Action and Persistence of Neuroprotection by Cell-Permeant Ca²⁺Chelators

1994 • 75 citations

Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background

2000 • 74 citations

Unipolar brush cells of the vestibulocerebellum: afferents and targets

2000 • 74 citations

Structure of chick chromosomal genes for calbindin and calretinin

1988 • 72 citations

The Cellular Basis for the Relative Resistance of Parvalbumin and Calretinin Immunoreactive Neocortical Neurons to the Pathology of Alzheimer's Disease

1997 • 72 citations

Stellate cell inhibition of Purkinje cells in the turtle cerebellum in vitro.

1992 • 71 citations

Immunocytochemical localization of the plasma membrane calcium pump, calbindin-D28k, and parvalbumin in Purkinje cells of avian and mammalian cerebellum.

1993 • 70 citations

Developmental Changes in the Subcellular Localization of Calretinin

2000 • 69 citations

Reduced immunoreactivity to calcium-binding proteins in Purkinje cells precedes onset of ataxia in spinocerebellar ataxia-1 transgenic mice

1998 • 69 citations

Tetanus relaxation of fast skeletal muscles of the mouse made parvalbumin deficient by gene inactivation

2000 • 62 citations

Calcium-binding proteins in the retina of a calbindin-null mutant mouse

1998 • 61 citations

Mapping of the colocalization of calretinin and tyrosine hydroxylase in the rat substantia nigra and ventral tegmental area

1994 • 57 citations

Mechanisms of glutamate‐stimulated Mg2+ influx and subsequent Mg2+ efflux in rat forebrain neurones in culture.

1996 • 54 citations

Intracellular concentration of parvalbumin in nerve cells

1993 • 53 citations

Glutamatergic synaptic responses and long-term potentiation are impaired in the CA1 hippocampal area of calbindin D28k-deficient mice

1999 • 52 citations

Calcium binding by chick calretinin and rat calbindin D28k synthesised in bacteria

1993 • 50 citations

Calbindin-D28k in nerve cell nuclei

1997 • 50 citations

Calbindin_28kDa and calbindin_30kDa (calretinin) are substantially localised in the particulate fraction of rat brain

1995 • 49 citations

Postsynaptic and presynaptic effects of the calcium chelator BAPTA on synaptic transmission in rat hippocampal dentate granule neurons

1991 • 49 citations

Calretinin-immunoreactive neurons are resistant to β-amyloid toxicity in vitro

1995 • 48 citations

Inhibition of the Proliferative Cycle and Apoptotic Events in WiDr Cells after Down-Regulation of the Calcium-Binding Protein Calretinin Using Antisense Oligodeoxynucleotides

1996 • 47 citations

Inhibition of mitochondrial calcium uptake slows down relaxation in mitochondria-rich skeletal muscles.

1997 • 46 citations

Calcium‐dependent inactivation of high‐threshold calcium currents in human dentate gyrus granule cells

1998 • 44 citations

The calcium pump of the plasma membrane: membrane targeting, calcium binding sites, tissue-specific isoform expression.

1998 • 44 citations

Free intracellular Mg²⁺ concentration and inhibition of NMDA responses in cultured rat neurons

2001 • 41 citations

Differential Ca2+ binding properties in the human cerebellar cortex: distribution of parvalbumin and calbindin D-28k immunoreactivity

1992 • 39 citations

Purkinje neurons express the SERCA3 isoform of the organellar type Ca2+-transport ATPase

1996 • 38 citations

Chick Calretinin: Purification, Composition, and Metal Binding Activity of Native and Recombinant Forms

1997 • 36 citations

Membrane-Associated Vitamin D-Induced Calcium-Binding Protein (CaBP): Quantification by a Radioimmunoassay and Evidence for a Specific CaBP in Purified Intestinal Brush Borders^*

1984 • 33 citations

Decreased parvalbumin immunoreactivity in surviving Purkinje cells of patients with spinocerebellar ataxia-1

1996 • 31 citations

Poor correlation between delayed neuronal death induced by transient forebrain ischemia, and immunoreactivity for parvalbumin and calbindin D-28k in developing gerbil hippocampus

1994 • 31 citations

Relationship between ataxin-1 nuclear inclusions and Purkinje cell specific proteins in SCA-1 transgenic mice

2000 • 29 citations

The Molecular Biology of the Na⁺‐Ca²⁺ Exchanger and Its Functional Roles in Heart, Smooth Muscle Cells, Neurons, Glia, Lymphocytes, and Nonexcitable Cells^a

1996 • 29 citations

Association between the Calcium-Binding Protein Calretinin and Cytoskeletal Components in the Human Colon Adenocarcinoma Cell Line WiDr

2000 • 29 citations

The expression of calretinin in transfected PC12 cells provides no protection against Ca2+-overload or trophic factor deprivation

1996 • 29 citations

Evidence for a membrane-bound fraction of chick intestinal calcium-binding protein

1978 • 27 citations

Calretinin-Containing Neurons in Rat Cerebellar Granule Cell Cultures

1997 • 24 citations

Apparent Ca²⁺ dissociation constant of Ca²⁺ chelators incorporated non‐disruptively into intact human red cells

1997 • 21 citations

Ultrastructural localization of calretinin immunoreactivity in lobule V of the rat cerebellum

1993 • 21 citations

Neuroprotective properties of calretinin against the HIV-1 gp120 toxicity

1996 • 17 citations

Calmodulin binding to the intestinal brush-border membrane: Comparison to other calcium-binding proteins

1989 • 17 citations

Measurements of [Ca2+] using fura-2 in glioma C6 cells expressing calretinin with GFP as a marker of transfection: no Ca2+-buffering provided by calretinin

1999 • 17 citations

Calbindin 28kDa is specifically associated with extranuclear constituents of the dense particulate fraction

2000 • 15 citations

Evidence for calcium mediated conformational changes in calbindin-D28K (the vitamin D-induced calcium binding protein) interactions with chick intestinal brush border membrane alkaline phosphatase as studied via photoaffinity labeling techniques

1993 • 14 citations

Electrophysiological behavior of Purkinje cells and motor coordination in calretinin knock-out mice

2000 • 13 citations

Intracellular Ca²⁺release by InsP₃ in cerebellar Purkinje neurones

1996 • 8 citations

[Isolation of a parvalbumin from rabbit muscle].

1974 • 5 citations