Defects in Sensory and Autonomic Ganglia and Absence of Locus Coeruleus in Mice Deficient for the Homeobox Gene Phox2a

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

1994 • 1,589 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Requirement for neuregulin receptor erbB2 in neural and cardiac development

1995 • 1,272 citations

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 • 1,261 citations

Renal and neuronal abnormalities in mice lacking GDNF

1996 • 1,260 citations

The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary.

1996 • 1,208 citations

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

1996 • 1,208 citations

GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF

1996 • 1,170 citations

Characterization of a multicomponent receptor for GDNF

1996 • 1,086 citations

Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes

1994 • 1,005 citations

Expression of the c-ret proto-oncogene during mouse embryogenesis

1993 • 831 citations

GDNF signalling through the Ret receptor tyrosine kinase

1996 • 809 citations

Functional receptor for GDNF encoded by the c-ret proto-oncogene

1996 • 795 citations

Requirement for LIM Homeobox Gene Isl1 in Motor Neuron Generation Reveals a Motor Neuron– Dependent Step in Interneuron Differentiation

1996 • 774 citations

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

1995 • 686 citations

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1995 • 659 citations

Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons.

1995 • 595 citations

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1995 • 593 citations

Role of transcription factors a Brn-3.1 and Brn-3.2 in auditory and visual system development

1996 • 513 citations

Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts

1996 • 409 citations

GDNF is an age-specific survival factor for sensory and autonomic neurons

1995 • 401 citations

Guidebook to the homeobox genes

1994 • 399 citations

Initial tract formation in the mouse brain

1993 • 391 citations

Two rhombomeres are altered in Hoxa-1 mutant mice

1993 • 391 citations

GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo

1995 • 367 citations

POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells.

1996 • 336 citations

Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish

1995 • 290 citations

The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype

1993 • 290 citations

The Expression Pattern of the Transcription Factor Phox2 Delineates Synaptic Pathways of the Autonomic Nervous System

1996 • 287 citations

Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve

1996 • 282 citations

Development and survival of the endocrine hypothalamus and posterior pituitary gland requires the neuronal POU domain factor Brn-2.

1995 • 274 citations

Guidebook to the Homeobox Genes

1995 • 270 citations

Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein

1994 • 262 citations

The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse.

1995 • 259 citations

The dopamine β-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice

1991 • 251 citations

Differential expression of two neuronal intermediate-filament proteins, peripherin and the low-molecular-mass neurofilament protein (NF-L), during the development of the rat

1990 • 250 citations

Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence

1996 • 225 citations

C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons

1992 • 177 citations

Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons

1995 • 152 citations

Development of the rat superior cervical ganglion: ganglion cell maturation

1985 • 147 citations

1 Homeobox Gene Expression during Development of the Vertebrate Brain

1994 • 131 citations

Expression of the unc-4 homeoprotein in Caenorhabditis elegans motor neurons specifies presynaptic input

1995 • 114 citations

Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling

1996 • 112 citations

Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2.

1992 • 105 citations

A homeodomain protein selectively expressed in noradrenergic tissue regulates transcription of neurotransmitter biosynthetic genes

1995 • 103 citations

Transient expression of selected catecholaminergic traits in cranial sensory and dorsal root ganglia of the embryonic rat

1984 • 101 citations

The expression of tyrosine hydroxylase and the transcription factors cPhox-2 and Cash-1: evidence for distinct inductive steps in the differentiation of chick sympathetic precursor cells

1995 • 100 citations

Regulation of vertebrate neural cell fate by transcription factors

1996 • 81 citations

Some neuronal cell populations express human dopamine β-hydroxylase-lacZ transgenes transiently during embryonic development

1991 • 73 citations

Expression of ret in the chicken embryo suggests roles in regionalisation of the vagal neural tube and somites and in development of multiple neural crest and placodal lineages

1995 • 68 citations

A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development

1995 • 63 citations

The specification of sensory neuron identity in Drosophila

1993 • 43 citations

A possible link between cell adhesion receptors, homeodomain proteins and neuronal identity.

1993 • 14 citations