The Cellular C1 Factor of the Herpes Simplex Virus Enhancer Complex Is a Family of Polypeptides

Basic local alignment search tool

1990 • 87,358 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Current protocols in molecular biology

1988 • 4,543 citations

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

1980 • 1,256 citations

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1994 • 994 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

1994 • 668 citations

Associations between distinct pre-mRNA splicing components and the cell nucleus.

1991 • 523 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

An octamer oligonucleotide upstream of a TATA motif is sufficient for lymphoid-specific promoter activity

1987 • 398 citations

Reversal of terminal differentiation and control of DNA replication: Cyclin A and cdk2 specifically localize at subnuclear sites of DNA replication

1993 • 389 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins.

1988 • 381 citations

Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation

1988 • 377 citations

A complex formed between cell components and an HSV structural polypeptide binds to a viral immediate early gene regulatory DNA sequence

1988 • 360 citations

Generation of p50 subunit of NF-kB by processing of p105 through an ATP-dependent pathway

1991 • 316 citations

The POU domain is a bipartite DNA-binding structure

1988 • 304 citations

Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication.

1994 • 271 citations

Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication

1986 • 256 citations

The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein.

1989 • 245 citations

The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein

1993 • 241 citations

Cell-cycle regulation of a human histone H2b gene is mediated by the H2b subtype-specific consensus element.

1988 • 234 citations

Interactions of the Oct-1 POU subdomains with specific DNA sequences and with the HSV alpha-trans-activator protein.

1990 • 227 citations

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter

1992 • 225 citations

Arginine/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing

1991 • 224 citations

A common octamer motif binding protein is involved in the transcription of U6 snRNA by RNA polymerase III and U2 snRNA by RNA polymerase II

1987 • 224 citations

Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.

1988 • 221 citations

Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1-infected cells to its cis site requires cellular proteins.

1987 • 217 citations

Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1).

1994 • 199 citations

Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes.

1992 • 179 citations

Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene.

1986 • 157 citations

Transcription factor Oct-2A contains functionally redundant activating domains and works selectively from a promoter but not from a remote enhancer position in non-lymphoid (HeLa) cells.

1990 • 146 citations

Separation of sequences defining basal expression from those conferring alpha gene recognition within the regulatory domains of herpes simplex virus 1 alpha genes.

1984 • 140 citations

The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.

1990 • 139 citations

Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei.

1994 • 135 citations

The oct-1 homeo domain contacts only part of the octamer sequence and full oct-1 DNA-binding activity requires the POU-specific domain.

1990 • 135 citations

A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain.

1992 • 134 citations

Octamer-binding proteins from B or HeLa cells stimulate transcription of the immunoglobulin heavy-chain promoter in vitro.

1988 • 132 citations

The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: evidence for a homeo domain recognition subdomain.

1991 • 128 citations

Activation of octamer-containing promoters by either octamer-binding transcription factor 1 (OTF-1) or OTF-2 and requirement of an additional B-cell-specific component for optimal transcription of immunoglobulin promoters.

1990 • 117 citations

Characterization of a cellular factor which interacts functionally with Oct-1 in the assembly of a multicomponent transcription complex

1990 • 116 citations

Recognition of the surface of a homeo domain protein.

1992 • 115 citations

Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

1993 • 110 citations

Promoter and enhancer elements containing a conserved sequence motif are recognized by nuclear factor III, a protein stimulating adenovirus DNA replication.

1987 • 110 citations

A cellular factor binds to the herpes simplex virus type 1 transactivator Vmw65 and is required for Vmw65-dependent protein-DNA complex assembly with Oct-1.

1990 • 109 citations

A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA.

1993 • 108 citations

Purified octamer binding transcription factors stimulate RNA polymerase III-mediated transcription of the 7SK RNA gene

1989 • 108 citations

Distinct factors with Sp1 and NF-A specificities bind to adjacent functional elements of the human U2 snRNA gene enhancer.

1987 • 106 citations

A distant enhancer element is required for polymerase III transcription of a U6 RNA gene

1987 • 102 citations

Purification of the cellular C1 factor required for the stable recognition of the Oct-1 homeodomain by the herpes simplex virus alpha-trans-induction factor (VP16).

1993 • 98 citations

Replication and transcription sites are colocalized in human cells

1994 • 96 citations

Cell-type-specific transcription of an immunoglobulin kappa light chain gene in vitro.

1986 • 96 citations

Purification and characterization of nuclear factor III (origin recognition protein C), a sequence-specific DNA binding protein required for efficient initiation of adenovirus DNA replication.

1988 • 93 citations

The promoter of the human interleukin-2 gene contains two octamer-binding sites and is partially activated by the expression of Oct-2.

1990 • 91 citations

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

1993 • 88 citations

Histone H1 subtype-specific consensus elements mediate cell cycle-regulated transcription in vitro.

1989 • 88 citations

Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1

1988 • 66 citations

Both Oct-1 and Oct-2A contain domains which can activate the ubiquitously expressed U2 snRNA genes.

1991 • 31 citations

Identification of a domain of the herpes simplex virus trans-activator Vmw65 required for protein-DNA complex formation through the use of protein A fusion proteins

1989 • 24 citations