Forskolin-stimulated platelet adenylyl cyclase activity is lower in persons with major depression

An Inventory for Measuring Depression

1961 • 36,954 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

THE CATECHOLAMINE HYPOTHESIS OF AFFECTIVE DISORDERS: A REVIEW OF SUPPORTING EVIDENCE

1965 • 3,421 citations

A new, semi-structured psychiatric interview for use in genetic linkage studies: a report on the reliability of the SSAGA.

1994 • 1,757 citations

One-Month Prevalence of Mental Disorders in the United States

1988 • 1,755 citations

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

1981 • 1,655 citations

Receptor-effector coupling by G proteins

1990 • 1,117 citations

Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein.

1981 • 735 citations

The alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability of alcohol and drug modules in a general population sample

1995 • 703 citations

Epidemiology of depression in primary care

1992 • 692 citations

Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey

1995 • 638 citations

GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4

1994 • 564 citations

The Bicinchoninic Acid (BCA) Assay for Protein Quantitation

2003 • 529 citations

Type VIII adenylyl cyclase. A Ca2+/calmodulin-stimulated enzyme expressed in discrete regions of rat brain.

1994 • 360 citations

Molecular and functional diversity of mammalian G _s ‐stimulated adenylyl cyclases

1993 • 295 citations

A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits

1995 • 276 citations

The Beck Depression Inventory as a Screening Device for Major Depression in Renal Dialysis Patients

1989 • 251 citations

The platelets physiology and pharmacology

1986 • 203 citations

Guanosine Triphosphate Activation of Brain Adenylate Cyclase: Enhancement by Long-Term Antidepressant Treatment

1983 • 142 citations

Adenylyl cyclase activity and G-protein subunit levels in postmortem frontal cortex of suicide victims

1994 • 136 citations

Influence of sodium on the alpha 2-adrenergic receptor system of human platelets. Role for intraplatelet sodium in receptor binding.

1983 • 112 citations

Chronic Electroconvulsive Treatment Augments Coupling of the GTP‐Binding Protein G_s to the Catalytic Moiety of Adenylyl Cyclase in a Manner Similar to That Seen with Chronic Antidepressant Drugs

1991 • 110 citations

Platelets as Pharmacologic Models for the Receptors and Biochemistry of Monoaminergic Neurons

1985 • 107 citations

Human blood platelet monoamine oxidase

1971 • 106 citations

The Platelets : physiology and pharmacology

1985 • 104 citations

Control of a Novel Adenylyl Cyclase by Calcineurin

1995 • 98 citations

Platelet alpha-adrenergic binding and biochemical responsiveness in depressed patients and controls

1984 • 88 citations

A comparison of DSM‐III‐R, DSM‐IV and ICD‐10 substance use disorders diagnoses in 1922 men and women subjects in the COGA study

1994 • 85 citations

The Bicinchoninic Acid (BCA) Assay for Protein Quantitation

2003 • 85 citations

The Clinical and Financial Burden of Mood Disorders

1995 • 84 citations

mu-Opioid receptors inhibit dopamine-stimulated activity of type V adenylyl cyclase but enhance dopamine-stimulated activity of type VII adenylyl cyclase.

1996 • 84 citations

Coupling of the stimulatory GTP-binding protein Gs to rat synaptic membrane adenylate cyclase is enhanced subsequent to chronic antidepressant treatment.

1989 • 81 citations

A Novel Adenylyl Cyclase Sequence Cloned from the Human Erythroleukemia Cell Line

1993 • 78 citations

Chronic antidepressant treatment facilitates G protein activation of adenylyl cyclase without altering G protein content.

1995 • 78 citations

The Characterization of a Novel Human Adenylyl Cyclase Which Is Present in Brain and Other Tissues

1995 • 78 citations

α2-Adrenoceptor—Mediated Inhibition of Platelet Adenylate Cyclase and Induction of Aggregation in Major Depression

1990 • 75 citations

Childhood movement disorders and obsessive compulsive disorder.

1994 • 68 citations

Frontiers in Neuropsychiatric Research

1983 • 65 citations

Harakiri: a clinical study of deliberate self-stabbing.

1994 • 61 citations

Forskolin-activated adenylate cyclase. Inhibition by guanyl-5'-yl imidodiphosphate.

1983 • 59 citations

Platelet adenylate cyclase responses in depression: Implications for a receptor defect

1974 • 49 citations

The effects of Ca2+ and calmodulin on adenylyl cyclase activity in plasma membranes derived from neural and non-neural cells

1992 • 46 citations

Binding of [3H]forskolin to human platelet membranes. Regulation by guanyl-5'-yl imidodiphosphate, NaF, and prostaglandins E1 and D2.

1986 • 43 citations

Imbalance of the Gs and Gi/o function in post-mortem human brain of depressed patients

1993 • 43 citations

Catecholamine Receptor Function in Depressed Patients

1974 • 42 citations

Regulation of Mammalian Adenylyl Cyclases by G-Protein and Subunits

1992 • 38 citations

Measurement of protein using flow injection analysis with bicinchoninic acid

1987 • 37 citations

Inhibitory effects of sodium and other monovalent cations on human platelet adenylate cyclase.

1981 • 35 citations

The natural history and heterogeneity of depressive disorders: implications for rational antidepressant therapy.

1994 • 32 citations

Chemical and functional analysis of components of adenylyl cyclase from human platelets treated with phorbolesters

1991 • 30 citations

Platelet alpha-adrenergic receptor function in affective disorders and schizophrenia.

1985 • 30 citations

GTP-binding proteins and platelet activation.

1991 • 28 citations

Alpha2-adrenergic receptor function in patients with unipolar and bipolar affective disorders

1986 • 27 citations

Enhanced signal transduction by adenylate cyclase in platelet membranes of patients showing antidepressant responses to alprazolam: Preliminary data

1985 • 26 citations

Direct influence of antidepressants on GTP binding protein of adenylate cyclase in cell membranes of the cerebral cortex of rats

1988 • 21 citations

BLOOD PLATELETS AS A MODEL SYSTEM FOR STUDYING SEROTONERGIC DYSFUNCTION AND EFFECTS OF Antidepressants

1990 • 19 citations

Modulation of second messenger function in rat brain by in vivo alteration of receptor sensitivity: Relevance to the mechanism of action of electroconvulisve therapy and antidepressants

1989 • 19 citations

Platelet adenylate cyclase activity in depression and after clomipramine and lithium treatment: relation to serotonergic function

1992 • 17 citations

Platelet alpha2-adrenergic receptor function in psychiatric disorders

1988 • 16 citations

Effect of long-term clorgyline administration on human platelet alpha-adrenergic receptor binding and platelet cyclic AMP responses

1983 • 16 citations

GTP-binding proteins and platelet activation.

1991 • 14 citations

Platelet alpha-adrenergic receptor function in affective disorders and schizophrenia.

1985 • 13 citations

Evidence for regulation of human platelet adenylate cyclase by phosphorylation. Inhibition by ATP and guanosine 5′-[β-thio]diphosphate occur by distinct mechanisms

1991 • 13 citations

Platelet adrenoceptors and prostaglandin responses in depressed patients

1989 • 10 citations

Decrease in Epinephrine-lnduced Attenuation of Platelet Adenylate Cyclase Activity in Depressed Patients: Relation with Plasma Electrolytes

1992 • 6 citations