Effect of Purified Allicin, the Major Ingredient ofFreshly Crushed Garlic, on Cancer Cell Proliferation

Arzneimittelforschung

2005 • 8,820 citations

[70] Determination of glutathione and glutathione disulfide in biological samples

1985 • 2,678 citations

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

1993 • 1,888 citations

Therapeutic actions of garlic constituents

1996 • 664 citations

Role of Oxidants and Antioxidants in the Induction of AP-1, NF-κB, and Glutathione S-Transferase Gene Expression

1996 • 457 citations

The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins

1998 • 409 citations

Endogenous glutathione conjugates: occurrence and biological functions.

1998 • 400 citations

Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death

1998 • 345 citations

The mode of action of allicin: its ready permeability through phospholipid membranes may contribute to its biological activity

2000 • 337 citations

Antioxidant activity of allicin, an active principle in garlic

1995 • 242 citations

Garlic Chemistry: Stability of S-(2-Propenyl)-2-Propene-1-sulfinothioate (Allicin) in Blood, Solvents, and Simulated Physiological Fluids

1995 • 239 citations

Enzyme inhibition by allicin, the active principle of garlic

1956 • 223 citations

Differential inhibitory effects of garlic‐derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures

1996 • 206 citations

Ajoene, a Compound of Garlic, Induces Apoptosis in Human Promyeloleukemic Cells, Accompanied by Generation of Reactive Oxygen Species and Activation of Nuclear Factor κB

1998 • 205 citations

Non-oxidative Loss of Glutathione in Apoptosis via GSH Extrusion

1995 • 190 citations

Impact of organosulfur compounds in garlic on canine mammary tumor cells in culture

1993 • 132 citations

Antiproliferative effect of the garlic compound S-allyl cysteine on human neuroblastoma cells in vitro

1992 • 130 citations

Antiplatelet constituents of garlic and onion

1990 • 117 citations

Effects of garlic thioallyl derivatives on growth, glutathione concentration, and polyamine formation of human prostate carcinoma cells in culture

1997 • 117 citations

S‐allylmercaptocysteine inhibits cell proliferation and reduces the viability of erythroleukemia, breast, and prostate cancer cell lines

1997 • 102 citations

Initial study on naturally occurring products from traditional Chinese herbs and vegetables for chemoprevention

1997 • 101 citations

The effects of garlic preparations against human tumor cell proliferation

1999 • 96 citations

The cytotoxic effect of ajoene, a natural product from garlic, investigated with different cell lines

1990 • 95 citations

Alteration of lipid profile in hyperlipidemic rabbits by allicin, an active constituent of garlic.

1995 • 79 citations

Aged garlic extract modulates glutathione redox cycle and superoxide dismutase activity in vascular endothelial cells

1997 • 68 citations

Metabolism of diallyl disulfide by human liver microsomal cytochromes P-450 and flavin-containing monooxygenases.

1999 • 67 citations

Thioallyl compounds: Potent inhibitors of cell proliferation

1994 • 52 citations

Relationship of glutathione and glutathione-S-transferase to cisplatin sensitivity in human head and neck squamous carcinoma cell lines

1994 • 45 citations

[The pharmacokinetics of the S35 labeled labeled garlic constituents alliin, allicin and vinyldithiine].

1994 • 44 citations

Analysis of responses of allicin, a compound from garlic, in the pulmonary vascular bed of the cat and in the rat

1995 • 35 citations

Reducing effects of garlic constituents on DNA adduct formation in human lymphocytesin vitro

1997 • 33 citations

[16] Noninvasive measurement of thiol levels in cellsand isolated organs

1995 • 27 citations

Effects of ?-valine on growth and polyamine metabolism in human colon carcinoma cells

1998 • 19 citations

Allicin-Induced Hypotension in Rabbit Eyes

1993 • 18 citations

Inhibition of GSH-dependent PGH2 isomerase in mammary adenocarcinoma cells by allicin.

1989 • 14 citations

Comments on Garlic Chemistry: Stability of S-(2-Propenyl) 2-Propene-1-sulfinothioate (Allicin) in Blood, Solvents, and Simulated Physiological Fluids

1997 • 11 citations

Aged garlic extract modulates glutathione redox cycle and superoxide dismutase activity in vascular endothelial cells

1997 • 11 citations

Initial study on naturally occurring products from traditional Chinese herbs and vegetables for chemoprevention

1997 • 5 citations

Modification of catalytic properties of chicken liver fructose 1,6-bisphosphatase by allicin.

1993 • 5 citations