Sense and antisense transcripts of the developmentally regulated murine hsp70.2 gene are expressed in distinct and only partially overlapping areas in the adult brain

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

Cells in Stress: Transcriptional Activation of Heat Shock Genes

1993 • 1,429 citations

The Biology of heat shock proteins and molecular chaperones.

1994 • 1,226 citations

Mammalian stress response: cell physiology, structure/function of stress proteins, and implications for medicine and disease

1992 • 1,201 citations

Stress protein systems of mammalian cells

1986 • 564 citations

Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

1993 • 469 citations

Localization of 70-kDa stress protein induction in gerbil brain after ischemia

1988 • 465 citations

Heat shock proteins, first major products of zygotic gene activity in mouse embryo

1983 • 401 citations

Hoxa 11 structure, extensive antisense transcription, and function in male and female fertility

1995 • 390 citations

Intragenic pausing and anti-sense transcription within the murine c-myc locus.

1986 • 326 citations

A novel member of the thyroid/steroid hormone receptor family is encoded by the opposite strand of the rat c-erbA alpha transcriptional unit.

1989 • 316 citations

An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes

1989 • 305 citations

Heat shock proteins as markers of neural injury

1989 • 304 citations

Two erbA homologs encoding proteins with different T3 binding capacities are transcribed from opposite DNA strands of the same genetic locus

1989 • 251 citations

Developmental and spatial patterns of expression of the mouse homeobox gene, Hox2.1

1987 • 232 citations

Antisense RNA: its functions and applications in gene regulation — a review

1988 • 230 citations

Protein and peptide binding and stimulation of in vitro lysosomal proteolysis by the 73-kDa heat shock cognate protein.

1992 • 201 citations

Two Mammalian Genes Transcribed from Opposite Strands of the Same DNA Locus

1987 • 195 citations

Identification and sequence analysis of a new member of the mouse HSP70 gene family and characterization of its unique cellular and developmental pattern of expression in the male germ line.

1988 • 184 citations

Induction of a heat shock gene at the site of tissue injury in the rat brain

1989 • 183 citations

Induction of stress protein HSP70 in nerve cells after status epilepticus in the rat

1989 • 179 citations

Altered expression of heat shock proteins in embryonal carcinoma and mouse early embryonic cells.

1984 • 173 citations

N-myc mRNA Forms an RNA-RNA Duplex with Endogenous Antisense Transcripts

1990 • 173 citations

Induction of heat shock (stress) genes in the mammalian brain by hyperthermia and other traumatic events: A current perspective

1990 • 170 citations

Gene regulation: Biology of antisense RNA and DNA

1992 • 146 citations

Selective induction of a heat shock gene in fibre tracts and cerebellar neurons of the rabbit brain detected by in situ hybridization

1987 • 145 citations

Hypoxia—ischemia induces heat shock protein-like (HSP72) immunoreactivity in neonatal rat brain

1990 • 139 citations

Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia

1991 • 131 citations

N-myc mRNA forms an RNA-RNA duplex with endogenous antisense transcripts.

1990 • 129 citations

Expression of Heat Shock Protein 70 and Heat Shock Cognate 70 Messenger RNAs in Rat Cortex and Cerebellum After Heat Shock or Amphetamine Treatment

1991 • 115 citations

Gene regulation : biology of antisense RNA and DNA

1992 • 106 citations

cDNA cloning and expression of stress‐inducible rat hsp70 normal and injured rat brain

1993 • 105 citations

Mammalian heat shock protein families. Expression and functions

1992 • 105 citations

Identification of the gene for the developmentally expressed 70 kDa heat-shock protein (P70) of mouse spermatogenic cells

1992 • 100 citations

Analysis of beta 2-microglobulin gene expression in the developing mouse embryo and placenta.

1990 • 96 citations

Heat shock proteins in the nervous system

1994 • 91 citations

In vivo hyperthermia induces expression of HSP70 mRNA in brain regions controlling the neuroendocrine response to stress

1990 • 84 citations

Expression of heat shock genes (hsp70) in the mammalian brain: Distinguishing constitutively expressed and hyperthermia‐inducible mRNA species

1990 • 81 citations

The Drosophila micropia retrotransposon encodes a testis-specific antisense RNA complementary to reverse transcriptase.

1994 • 78 citations

Temporal and spatial distribution of heat shock mRNA and protein (hsp70) in the rabbit cerebellum in response to hyperthermia

1993 • 69 citations

Stage and lineage‐regulated expression of two HSP90 transcripts during mouse germ cell differentiation and embryogenesis

1991 • 66 citations

Heat shock gene expression and development. II. An overview of mammalian and avian developmental systems

1993 • 64 citations

Detection of Luteinizing Hormone β Messenger Ribonucleic Acid (RNA) in Individual Gonadotropes after Castration: Use of a Newin SituHybridization Method with a Photobiotinylated Complementary RNA Probe

1987 • 60 citations

Distributions of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient focal ischemia in rat brain

1992 • 52 citations

Post-transcriptional events are responsible for low expression of myelin basic protein in myelin deficient mice: role of natural antisense RNA.

1990 • 49 citations

Characterization and inducibility of hsp 70 proteins in the male mouse germ line.

1990 • 49 citations

Altered Expression of Heat Shock Proteins in Embryonal Carcinoma and Mouse Early Embryonic Cells

1984 • 48 citations

Processing of gonadotropin-releasing hormone gene transcripts in the rat brain.

1994 • 46 citations

Identification of antisense transcripts of the chicken insulin-like growth factor-II gene

1991 • 46 citations

Myelin Basic Protein Gene and the Function of Antisense RNA in Its Repression in Myelin‐Deficient Mutant Mouse

1991 • 46 citations

An antisense promoter of the murine c-myc gene is localized within intron 2.

1992 • 43 citations

Sex differences in the regulation of heat shock protein 70 kDa and 90 kDa in the rat ventromedial hypothalamus by estrogen

1992 • 35 citations

Distribution of constitutive- and hyperthermia-inducible heat shock mRNA species (hsp70) in the Purkinje layer of the rabbit cerebellum

1992 • 31 citations

Cellular localization of heat shock gene expression in rabbit cerebellum by in situ hybridization with plastic-embedded tissue

1989 • 31 citations

Widespread constitutive expression of HSP90 messenger RNA in rat brain

1993 • 29 citations

Identification of an antisense transcript from the IGF‐II locus in mouse

1993 • 27 citations

Distinct transcripts are recognized by sense and antisense riboprobes for a member of the murine HSP70 gene family, HSP70.2, in various reproductive tissues

1996 • 14 citations

Regulation of eukaryotic gene expression by natural antisense transcripts. The case of the modifying reaction.

1992 • 5 citations