A single point mutation of hamster aminoacyl‐tRNA synthetase causes apoptosis by deprivation of cognate amino acid residue

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.

1992 • 2,906 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

1992 • 2,495 citations

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme

1993 • 2,484 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Life, death, and the pursuit of apoptosis.

1996 • 1,333 citations

Molecular Cloning of the Interleukin-1β Converting Enzyme

1992 • 1,115 citations

Genetic Control of Programmed Cell Death in Drosophila

1994 • 1,028 citations

Prevention of Programmed Cell Death in Caenorhabditis elegans by Human bcl-2

1992 • 608 citations

The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

1992 • 387 citations

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells.

1993 • 223 citations

The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli

1995 • 125 citations

One-step growth cycle for BHK21/13 hamster fibroblasts

1970 • 98 citations

Molecular cloning of the cDNA of human X chromosomal gene (CCG1) which complements the temperature-sensitive G1 mutants, tsBN462 and ts13, of the BHK cell line.

1988 • 86 citations

Analysis of a method for selecting temperature-sensitive mutants of BHK cells

1978 • 85 citations

CHO cell mutants for arginyl-, asparagyl-, glutaminyl-, histidyl- and methionyl-transfer RNA synthetases: Identification and initial characterization

1977 • 75 citations

Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm.

1992 • 71 citations

Molecular cloning of a human gene that regulates chromosome condensation and is essential for cell proliferation.

1986 • 68 citations

[Genetic control of programmed cell death].

1996 • 64 citations

Large-scale selection and analysis of temperature-sensitive mutants for cell reproduction from BHK cells

1982 • 45 citations

Evidence for structural gene alterations affecting aminoacyl-tRNA synthetases in CHO cell mutants and revertants

1978 • 32 citations

Molecular cloning of the human gene, ccg2, that complements the bhk-derived temperature-sensitive cell cycle mutant tsbn63: Identity of ccg2 with the human x chromosomal scar/rps4x gene

1991 • 25 citations

A hamster temperature‐sensitive G1 mutant, tsBN250 has a single point mutation in histidyl‐tRNA synthetase that inhibits an accumulation of cyclin D1

1996 • 16 citations