The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

The embryonic cell lineage of the nematode Caenorhabditis elegans

1983 • 4,070 citations

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

1977 • 3,432 citations

The Nematode Caenorhabditis elegans

1988 • 2,868 citations

Mechanisms and Functions of Cell Death

1991 • 2,061 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Genetic control of programmed cell death in the nematode C. elegans

1986 • 1,790 citations

Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage

1988 • 1,745 citations

Calcium Dependence of Toxic Cell Death: A Final Common Pathway

1979 • 1,478 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

CELL DEATHS IN NORMAL VERTEBRATE ONTOGENY

1951 • 1,194 citations

Three-dimensional structure of calmodulin

1985 • 1,035 citations

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation.

1988 • 909 citations

FIBRINOGEN AND FIBRIN

1984 • 748 citations

Toward a physical map of the genome of the nematode Caenorhabditis elegans

1986 • 631 citations

mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans

1988 • 573 citations

Rapid confirmation and revision of the primary structure of bovine serum albumin by ESIMS and frit-FAB LC/MS

1990 • 552 citations

The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death

1990 • 533 citations

Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans.

1991 • 463 citations

The refined crystal structure of bovine β-trypsin at 1·8 Å resolution

1975 • 462 citations

Integrative transformation of Caenorhabditis elegans

1986 • 417 citations

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

1989 • 405 citations

Mutations Affecting Programmed Cell Deaths in the Nematode Caenorhabditis elegans s

1983 • 389 citations

A uniform genetic nomenclature for the nematode Caenorhabditis elegans

1979 • 382 citations

Troponin and Parvalbumin Calcium Binding Regions Predicted in Myosin Light Chain and T4 Lysozyme

1975 • 374 citations

The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. Molecular details, ion binding, and implications for the structure of other calcium-binding proteins.

1986 • 340 citations

The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors

1988 • 334 citations

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

1990 • 332 citations

Structure of vitamin D-dependent calcium-binding protein from bovine intestine

1981 • 309 citations

Extrachromosomal DNA Transformation of Caenorhabditis elegans

1985 • 306 citations

Molecular biology of the cytoskeleton

1984 • 296 citations

A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant

1987 • 280 citations

The amino acid sequence of rabbit skeletal muscle troponin C: Gene replication and homology with calcium ‐binding proteins from carp and hake muscle

1973 • 266 citations

Agonist-induced myopathy at the neuromuscular junction is mediated by calcium.

1979 • 242 citations

A novel calcium binding site in the galactose-binding protein of bacterial transport and chemotaxis

1987 • 238 citations

Sustained increase in intracellular calcium promotes neuronal survival

1991 • 213 citations

Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans

1987 • 192 citations

Calcium Coordination and the Calmodulin Fold: Divergent versus Convergent Evolution

1987 • 184 citations

Two C. elegans genes control the programmed deaths of specific cells in the pharynx

1991 • 171 citations

A new selective phage cloning vector, λ2001, with sites for XbaI, BamHI, HindIII, EcoRI, SstI and XhoI

1984 • 144 citations

Phage Lambda and Molecular Cloning

1983 • 135 citations

Morphology of programmed cell death in the ventral nerve cord of Caenorhabditis elegans larvae

1982 • 132 citations

Cell Death in Invertebrate Nervous Systems

1984 • 104 citations

Structural organization, DNA sequence, and expression of the calmodulin gene.

1988 • 103 citations

Localization of a fibrinogen calcium binding site between gamma-subunit positions 311 and 336 by terbium fluorescence.

1985 • 97 citations

Structure of a Calcium-Binding Carp Myogen

1972 • 92 citations

The Caenorhabditis elegans gene lin-10 is broadly expressed while required specifically for the determination of vulval cell fates.

1990 • 71 citations

The Primary Structure of the Major Parvalbumin from Hake Muscle

1973 • 63 citations

Demonstration of three distinct calcium-binding sites in villin, a modulator of actin assembly.

1983 • 55 citations

Partial inhibition of castration induced ventral prostate regression with actinomycin D and cycloheximide.

1978 • 55 citations

Tc4, a Caenorhabditis elegans transposable element with an unusual fold-back structure.

1991 • 51 citations

Location of specific messenger RNAs in Caenorhabditis elegans by cytological hybridization

1983 • 44 citations

Amino acid sequence of two sarcoplasmic calcium-binding proteins from the protochordate Amphioxus

1986 • 42 citations

AN AUTOSOMAL GENE THAT AFFECTS X CHROMOSOME EXPRESSION AND SEX DETERMINATION IN CAENORHABDITIS ELEGANS

1984 • 37 citations

The Amino-Acid Sequence of the Major Parvalbumin from Thornback-Ray Muscle

1977 • 32 citations

Mechanisms for Programmed Cell Death in the Nervous System of a Moth

2007 • 29 citations

On the nature of undead cells in the nematode Caenorhabditis elegans

1991 • 27 citations