Design, Synthesis, and Evaluation of 3,4-Dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as Inhibitors of Poly(ADP-Ribose) Polymerase

Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

1995 • 12,149 citations

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

1990 • 3,683 citations

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

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Role of poly(ADP-ribose) formation in DNA repair

1992 • 1,142 citations

Novel inhibitors of poly(ADP-ribose) synthetase

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Anticancer Chemosensitization and Radiosensitization by the Novel Poly(ADP-ribose) Polymerase-1 Inhibitor AG14361

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Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase.

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The 193-Kd Vault Protein, Vparp, Is a Novel Poly(Adp-Ribose) Polymerase

1999 • 386 citations

Involvement of poly(ADP-ribose) polymerase in base excision repair

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Molecular and biochemical features of poly (ADP-ribose) metabolism

1993 • 300 citations

Resistance-Modifying Agents. 9. Synthesis and Biological Properties of Benzimidazole Inhibitors of the DNA Repair Enzyme Poly(ADP-ribose) Polymerase

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Suppression of a myosin defect by a kinesin-related gene

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Role of Glutamic Acid 988 of Human Poly-ADP-ribose Polymerase in Polymer Formation

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Tricyclic Benzimidazoles as Potent Poly(ADP-ribose) Polymerase-1 Inhibitors

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A Human Poly(ADP-ribose) Polymerase Gene Family (ADPRTL): cDNA Cloning of Two Novel Poly(ADP-ribose) Polymerase Homologues

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Potential clinical applications of poly(ADP-ribose) polymerase (PARP) inhibitors

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Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro

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Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure

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Resistance-Modifying Agents. 5. Synthesis and Biological Properties of Quinazolinone Inhibitors of the DNA Repair Enzyme Poly(ADP-ribose) Polymerase (PARP)

1998 • 124 citations

Untitled

1976 • 65 citations

Synthesis of 3-Substituted Benzamides and 5-Substituted Isoquinolin-1(2H)-ones and Preliminary Evaluation as Inhibitors of Poly(ADP-ribose)polymerase (PARP)

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The determination of kinetic constants governing the slow,tight-binding inhibition of enzyme-catalysed reactions

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Improved aromatization of .alpha.-tetralone oximes to N- (1-naphthyl)acetamides

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PARP inhibition: a novel approach to treat ischaemia/reperfusion and inflammation-related injuries

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4-Substituted piperidines. V. Local anesthetic 4-aminoalkoxy-4-arylpiperidines

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