IPF _2α -I: An index of lipid peroxidation in humans

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1993 • 4,414 citations

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1996 • 2,163 citations

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.

1996 • 1,269 citations

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.

1992 • 742 citations

Prospective Study of Hemostatic Factors and Incidence of Coronary Heart Disease

1997 • 739 citations

Measurement of Plasma Hydroperoxide Concentrations by the Ferrous Oxidation-Xylenol Orange Assay in Conjunction with Triphenylphosphine

1994 • 657 citations

Modulation of Oxidant Stress In Vivo in Chronic Cigarette Smokers

1996 • 621 citations

Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment

1991 • 580 citations

Randomised trial of α-tocopherol and β-carotene supplements on incidence of major coronary events in men with previous myocardial infarction

1997 • 578 citations

Noncyclooxygenase oxidative formation of a series of novel prostaglandins: Analytical ramifications for measurement of eicosanoids

1990 • 480 citations

Isoprostanes: Potential Markers of Oxidant Stress in Atherothrombotic Disease

1997 • 461 citations

Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes.

1987 • 392 citations

Supplementation with vitamin E but not beta-carotene in vivo protects low density lipoprotein from lipid peroxidation in vitro. Effect of cigarette smoking.

1992 • 354 citations

Immunological characterization of urinary 8-epi-prostaglandin F2 alpha excretion in man.

1995 • 340 citations

11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation.

1986 • 281 citations

8-Epi PGF _2α Generation During Coronary Reperfusion

1997 • 272 citations

Cylooxygenase-dependent Formation of the Isoprostane, 8-Epi Prostaglandin F2α

1995 • 262 citations

Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells

1993 • 260 citations

[16] Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism

1994 • 225 citations

The F2-isoprostane, 8-epi-prostaglandin F2α, a potent agonist of the vascular thromboxane/endoperoxide receptor, is a platelet thromboxane/endoperoxide receptor antagonist

1992 • 214 citations

Increased Formation of the Isoprostanes IPF _2α -I and 8-Epi-Prostaglandin F _2α in Acute Coronary Angioplasty

1997 • 211 citations

Local Amplification of Platelet Function by 8-Epi Prostaglandin F2α Is Not Mediated by Thromboxane Receptor Isoforms

1996 • 205 citations

Generation of 8-Epiprostaglandin F by Human Monocytes

1996 • 189 citations

Evidence that the F2-isoprostane, 8-epi-prostaglandin F2α, is formed in vivo

1994 • 166 citations

Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine and plasma.

1993 • 158 citations

Effects of a novel prostaglandin, 8-epi-PGF2 alpha, in rabbit lung in situ

1992 • 127 citations

Recurrent ischemia in the canine heart causes recurrent bursts of free radical production that have a cumulative effect on contractile function. A pathophysiological basis for chronic myocardial "stunning".

1995 • 125 citations

8-Epi PGF_2α : specific analysis of an isoeicosanoid as an index of oxidant stress in vivo

1996 • 123 citations

Comparison of supplementation of RRR-alpha-tocopherol and racemic alpha-tocopherol in humans. Effects on lipid levels and lipoprotein susceptibility to oxidation.

1993 • 111 citations

Protein kinase A phosphorylation enhances sodium channel currents in Xenopus oocytes

1992 • 107 citations

Association Between Cigarette Smoking and Lipid Peroxidation in a Controlled Feeding Study

1997 • 107 citations

Vitamin E, LDL, and endothelium. Brief oral vitamin supplementation prevents oxidized LDL-mediated vascular injury in vitro.

1993 • 105 citations

Generation of the isoprostane 8-epi-prostaglandin F2alpha in vitro and in vivo via the cyclooxygenases.

1997 • 88 citations

Induction of prostaglandin endoperoxide synthase‐2 in human monocytes associated with cyclo‐oxygenase‐dependent F₂‐isoprostane formation

1996 • 76 citations

Preferential formation of 8-epi-prostaglandin f2α via the corresponding endoperoxide by a biomimetic cyclization

1984 • 69 citations

Mass spectrometric analysis of four regioisomers of F₂-isoprostanes formed by free radical oxidation of arachidonic acid

1996 • 63 citations

Reaction of dipyridamole with the hydroxyl radical

1992 • 62 citations

Identification of novel arachidonic acid metabolites formed by prostaglandin H synthase

1987 • 62 citations

Total Synthesis of 8-epi-PGF2.alpha.. A Novel Strategy for the Synthesis of Isoprostanes

1994 • 58 citations

Total synthesis of a novel isoprostane IPF2α-I and its identification in biological fluids

1996 • 56 citations

Enzymatic preparation of carboxyl oxygen-18 labeled prostaglandin F2α and utility for quantitative mass spectrometry

1981 • 55 citations

Protective effect of a new anti-oxidant on the rat brain exposed to ischemia-reperfusion injury: Inhibition of free radical formation and lipid peroxidation

1991 • 46 citations

Protection of low density lipoprotein oxidation at chemical and cellular level by the antioxidant drug dipyridamole

1996 • 46 citations

Enzymatic regulation of the prostaglandin response in a human model of inflammation

1996 • 3 citations