Interleukin-6 and TNFα production in human renal cell carcinoma

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

Production of hybridoma growth factor by human monocytes

1987 • 1,133 citations

Molecular Cloning of the Complementary DNA for Human Tumor Necrosis Factor

1985 • 633 citations

Peptide Regulatory Factors

1989 • 498 citations

Interleukin‐6 (IL‐6) functions as an in vitro autocrine growth factor in renal cell carcinomas

1989 • 420 citations

Cellular origin and differentiation of renal carcinomas. A fluorescence microscopic study with kidney-specific antibodies, antiintermediate filament antibodies, and lectins.

1983 • 359 citations

Biologic activities and mechanisms of action of tumor necrosis factor-alpha/cachectin.

1991 • 256 citations

MHC class II, antigen presentation and tumor necrosis factor in renal tubular epithelial cells

1990 • 246 citations

Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes.

1988 • 227 citations

Constitutive production of interleukin 6 by ovarian cancer cell lines and by primary ovarian tumor cultures.

1990 • 226 citations

IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell lines.

1989 • 205 citations

Assays for tumour necrosis factor and related cytokines

1989 • 204 citations

Tumor necrosis factor gene expression in human vascular intimal smooth muscle cells detected by in situ hybridization.

1990 • 184 citations

[Tumors of the kidney].

1952 • 177 citations

Cachectin (Tumor Necrosis Factor)

1988 • 170 citations

Recombinant 55-kDa tumor necrosis factor (TNF) receptor. Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity.

1991 • 154 citations

Stimulated kidney tubular epithelial cells express membrane associated and secreted TNFα

1991 • 151 citations

Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line.

1987 • 137 citations

Interleukin-6 immunoreactivity in human tumors.

1989 • 136 citations

Enhanced Expression of Interleukin-6 in Primary Human Renal Cell Carcinomas

1991 • 133 citations

Genes for IFN-beta-2 (IL-6), tumor necrosis factor, and IL-1 are expressed at high levels in the organs of normal individuals.

1988 • 119 citations

Human renal tubular cells as a cytokine source: PDGF-B, GM-CSF and IL-6 mRNA expression in vitro.

1993 • 111 citations

Expression of the human nephron differentiation molecules in renal cell carcinomas.

1990 • 111 citations

Distribution of interleukin-6 in normal and diseased human kidney.

1991 • 110 citations

Interleukin-6 and renal cell cancer: Production, regulation, and growth effects

1992 • 108 citations

Tumor necrosis factor expression in human epithelial tumor cell lines.

1988 • 102 citations

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

1988 • 83 citations

Histogenesis of renal cell carcinoma and renal oncocytoma: An immunohistochemical study

1988 • 72 citations

Investigation of cytokine gene expression in human colorectal cancer.

1990 • 71 citations

An immunoperoxidase study of renal cell carcinomas: Correlation with nuclear grade, cell type, and histologic pattern

1988 • 66 citations

B cell growth and differentiation induced by supernatants of transformed epithelial cell lines

1986 • 59 citations

Proximal renal tubular surface membrane antigens identified in primary and metastatic renal cell carcinomas.

1986 • 30 citations

Epidermal Growth Factor Receptor Gene Analysis in Renal Cell Carcinoma

1990 • 30 citations

Monoclonal antibodies in urologic oncology

1987 • 29 citations

Interferon‐gamma interrupts autocrine growth mediated by endogenous interleukin‐6 in renal‐cell carcinoma

1991 • 24 citations

Proximal Renal Tubular Surface Membrane Antigens Identified in Primary and Metastatic Renal Cell Carcinomas

1987 • 20 citations