Investigation of cytokine gene expression in human colorectal cancer.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Genomic sequencing.

1984 • 8,343 citations

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors.

1987 • 895 citations

The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases

1986 • 539 citations

Production of Lymphotoxin, a Bone-Resorbing Cytokine, by Cultured Human Myeloma Cells

1987 • 386 citations

Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP.

1988 • 261 citations

Tumor Necrosis Factors: Gene Structure and Biological Activities

1986 • 215 citations

Cancer of the rectum: An analysis of 1000 cases

1940 • 211 citations

In situ hybridization methods for the detection of somatostatin mRNA in tissue sections using antisense RNA probes

1986 • 207 citations

Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line.

1987 • 137 citations

Recombinant tumor necrosis factor: Species specificity for a variety of human and murine transformed cell lines

1986 • 100 citations

Paradoxical effects of tumour necrosis factor in experimental ovarian cancer

1989 • 94 citations

Tumor necrosis factor and lymphotoxin gene expression in human tumor cell lines.

1988 • 83 citations

Elevation of Infiltrating Mononuclear Phagocytes in Human Colorectal Tumors

1987 • 31 citations

Endogenous and exogenous TNF therapy (EET therapy): conceptual and experimental grounds.

1988 • 15 citations

Kinetics of interleukin 2 mRNA and protein produced in the human T-cell line Jurkat and the effect of cyclosporin A

1989 • 12 citations

Regulation of the Response to Tumor Necrosis Factor

2015 • 5 citations