Effect of colchicine analogs on the dissociation of .alpha..beta. tubulin into subunits: The locus of colchicine binding

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Identification of a gene for β-tubulin in aspergillus nidulans

1978 • 294 citations

Podophyllotoxin as a probe for the colchicine binding site of tubulin.

1977 • 231 citations

Kinetics and mechanism of colchicine binding to tubulin: evidence for ligand-induced conformational changes

1978 • 221 citations

CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered β-tubulin

1980 • 201 citations

Guanosinetriphosphatase activity of tubulin associated with microtubule assembly.

1977 • 174 citations

Interaction of tubulin with single ring analogs of colchicine

1982 • 143 citations

Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin

1982 • 137 citations

Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain.

1992 • 131 citations

Interaction of tubulin with bifunctional colchicine analogs: an equilibrium study

1984 • 108 citations

Interactions of a photoaffinity analog of GTP with the proteins of microtubules.

1977 • 68 citations

Effect of colchicine binding on the reversible dissociation of the tubulin dimer

1982 • 61 citations

Tubulin sequence region beta 155-174 is involved in binding exchangeable guanosine triphosphate.

1987 • 61 citations

Direct photoaffinity labeling of tubulin with colchicine.

1991 • 59 citations

Polymerization of the tubulin-colchicine complex and guanosine 5'-triphosphate hydrolysis

1982 • 57 citations

Kinetics of dissociation of the tubulin-colchicine complex. Complete reaction scheme and comparison to thermodynamic measurements.

1991 • 48 citations

Roles of colchicine rings B and C in the binding process to tubulin

1989 • 46 citations

Photoaffinity labeling of tubulin with (2-nitro-4-azidophenyl)deacetylcolchicine: direct evidence for two colchicine binding sites

1989 • 44 citations

A photoaffinity derivative of colchicine: 6'-(4'-azido-2'-nitrophenylamino)hexanoyldeacetylcolchicine. Photolabeling and location of the colchicine-binding site on the alpha-subunit of tubulin.

1985 • 44 citations

The ligand- and microtubule assembly-induced GTPase activity of purified calf brain tubulin

1981 • 43 citations

Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring C' of biphenyl analogs

1991 • 40 citations

Physical and spectroscopic methods for the evaluation of the interactions of antimitotic agents with tubulin

1991 • 33 citations

Spectroscopic and kinetic features of allocolchicine binding to tubulin

1989 • 31 citations

Reversible dimer dissociation of tubulin S and tubulin detected by fluorescence anisotropy

1992 • 29 citations

Tubulin dimer dissociation detected by fluorescence anisotropy

1989 • 29 citations

Linkage between ligand binding and control of tubulin conformation

1992 • 28 citations

Roles of ring C oxygens in the binding of colchicine to tubulin

1991 • 25 citations

The effects of colchicine analogues on the reaction of tubulin with iodo[14C]acetamide and N,N'-ethylenebis(iodoacetamide).

1985 • 24 citations

Monoclonal antibodies localize the exchangeable GTP‐binding site in β‐ and not α‐tubulins

1985 • 20 citations

Energy-transfer studies of the distance between the high-affinity metal binding site and the colchicine and 8-anilino-1-naphthalenesulfonic acid binding sites on calf brain tubulin

1988 • 14 citations

Evaluation of the stoichiometry and strength of chloroquine-porphyrin interactions by difference spectroscopy

1985 • 10 citations