CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered β-tubulin

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

1958 • 1,786 citations

Transmembrane control of the receptors on normal and tumor cells

1976 • 951 citations

Reduced permeability in CHO cells as a mechanism of resistance to colchicine

1974 • 695 citations

Production of mammalian somatic cell hybrids by means of polyethylene glycol treatment

1975 • 549 citations

Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol

1976 • 542 citations

[103a] The use of guanidinium chloride in the isolation of nucleic acids

1968 • 494 citations

Messenger RNA for myosin polypeptides: Isolation from single myogenic cell cultures

1977 • 417 citations

Biochemistry and Physiology of Microtubules

1976 • 331 citations

Characterization of microtubule assembly in porcine brain extracts by viscometry

1973 • 318 citations

Pleiotropic phenotype of colchicine‐resistant CHO cells: Cross‐resistance and collateral sensitivity

1976 • 314 citations

Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts.

1977 • 309 citations

Polyethylene glycol-induced mammalian cell hybridization: Effect of polyethylene glycol molecular weight and concentration

1976 • 300 citations

Identification of a gene for β-tubulin in aspergillus nidulans

1978 • 294 citations

Addition of colchicine-tubulin complex to microtubule ends: The mechanism of substoichiometric colchicine poisoning

1977 • 285 citations

Selection and characterization of eight phenotypically distinct lines of lectin-resistant chinese hamster ovary cells

1975 • 280 citations

Are Cytoplasmic Microtubules Heteropolymers?

1971 • 261 citations

The chromosomes of CHO, an aneuploid Chinese hamster cell line: G-band, C-band, and autoradiographic analyses

1973 • 249 citations

Mutations causing charge alterations in regulatory subunits of the cAMP-dependent protein kinase of cultured S49 lymphoma cells

1977 • 222 citations

Efficient fluorography of 3H and 14C on thin layers

1978 • 190 citations

Isolation and Partial Characterization of α- and β-Tubulin from Outer Doublets of Sea-Urchin Sperm and Microtubules of Chick-Embryo Brain

1973 • 162 citations

[54] High resolution one- and two-dimensional electrophoretic analysis of mitochondrial membrane polypeptides

1979 • 122 citations

Mechanism of action of vinblastine. Binding of [acetyl-₃H]-vinblastine to embryonic chick brain tubulin and tubulin from sea urchin sperm tail outer doublet microtubules

1975 • 111 citations

Comparison of the genomic organization of Kirsten and Harvey sarcoma viruses

1978 • 106 citations

A sensitive method for measuring polymerized and depolymerized forms of tubulin in tissues.

1977 • 100 citations

Evidence that griseofulvin binds to a microtubule associated protein

1977 • 95 citations

Mutants of chinese hamster ovary (cho) cells with altered colcemid-binding affinity

1979 • 85 citations

Phosphorylation of the 10-nm filament protein from Chinese hamster ovary cells.

1979 • 83 citations

Construction of a recombinant bacterial plasmid containing a chick pro-alpha2 collagen gene sequence.

1978 • 61 citations

Expression of transformation in cell hybrids. I. Isolation and application of density-inhibited Balb/3T3 cells deficient in hypoxanthine phosphoribosyltransferase and resistant to ouabain

1976 • 60 citations

A new dimension in suspension fusion techniques with polyethylene glycol

1977 • 45 citations

The determination of similarities in amino acid composition among proteins separated by two-dimensional gel electrophoresis

1978 • 22 citations