Roles of colchicine rings B and C in the binding process to tubulin

Measurement of protein-binding phenomena by gel filtration

1962 • 1,275 citations

A Text-Book of Physical Chemistry

1936 • 1,216 citations

Colchicine-binding protein of mammalian brain and its relation to microtubules

1968 • 1,140 citations

[27] Circular dichroism and optical rotatory dispersion of proteins and polypeptides

1973 • 547 citations

In vitro reconstitution of calf brain microtubules: effects of solution variables

1977 • 333 citations

Addition of colchicine-tubulin complex to microtubule ends: The mechanism of substoichiometric colchicine poisoning

1977 • 285 citations

The Chemical Characterization of Calf Brain Microtubule Protein Subunits

1973 • 225 citations

Kinetics and mechanism of colchicine binding to tubulin: evidence for ligand-induced conformational changes

1978 • 221 citations

Promotion of Fluorescence upon Binding of Colchicine to Tubulin

1974 • 218 citations

The fluorescence of lysozyme and lysozyme substrate complexes

1966 • 192 citations

Interaction of tubulin with single ring analogs of colchicine

1982 • 143 citations

Effect of antimitotic drugs on tubulin GTPase activity and self-assembly.

1979 • 142 citations

Molecular features of colchicine associated with antimitotic activity and inhibition of tubulin polymerization

1976 • 141 citations

Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin

1982 • 137 citations

Tubulin bound to colchicine forms polymers different from microtubules.

1982 • 109 citations

Interaction of tubulin with bifunctional colchicine analogs: an equilibrium study

1984 • 108 citations

Binding to tubulin of the colchicine analog 2-methoxy-5-(2', 3', 4'-trimethoxyphenyl)tropone. Thermodynamic and kinetic aspects.

1984 • 95 citations

Changes in the circular dichroic spectrum of colchicine associated with its binding to tubulin

1981 • 91 citations

Polymerization of the tubulin-colchicine complex: relation to microtubule assembly

1983 • 67 citations

A graphical correction procedure for inner filter effect in fluorescence quenching titrations

1979 • 65 citations

Conformational study of calf brain tubulin

1978 • 58 citations

Polymerization of the tubulin-colchicine complex and guanosine 5'-triphosphate hydrolysis

1982 • 57 citations

Stereochemistry of Diphenyls. XXXI.¹ Preparation and Properties of 2,2',6,6'-Tetrafluoro-3,3'-dicarboxy-5,5'-dichlorodiphenyl

1933 • 47 citations

The ligand- and microtubule assembly-induced GTPase activity of purified calf brain tubulin

1981 • 43 citations

Über die Umlagerung des Colchicins mit Natriumalkoholat und die Struktur des Ringes C

1950 • 40 citations

Arylation of Unsaturated Systems by Free Radicals. I. Arylation of Alkylbenzenes

1955 • 25 citations

Binding of gossypol to purified tubulin and inhibition of its assembly into microtubules

1986 • 19 citations

Resonance Raman spectra of colchicinoids: free and bound to tubulin

1987 • 18 citations

[18] Measurement of protein-ligand interactions by gel chromatography

1985 • 15 citations

Synthesis and Binding to Tubulin of an Allocolchicine Spin Probe.

1981 • 11 citations