Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin

Linked Functions and Reciprocal Effects in Hemoglobin: A Second Look

1964 • 1,613 citations

Measurement of protein-binding phenomena by gel filtration

1962 • 1,275 citations

The stabilization of proteins by sucrose.

1981 • 1,084 citations

PURIFICATION OF TUBULIN AND ASSOCIATED HIGH MOLECULAR WEIGHT PROTEINS FROM PORCINE BRAIN AND CHARACTERIZATION OF MICROTUBULE ASSEMBLY IN VITRO*

1975 • 423 citations

Nucleotide and corresponding amino acid sequences encoded by α and β tubulin mRNAs

1981 • 380 citations

In vitro reconstitution of calf brain microtubules: effects of solution variables

1977 • 333 citations

Characterization of microtubule assembly in porcine brain extracts by viscometry

1973 • 318 citations

Addition of colchicine-tubulin complex to microtubule ends: The mechanism of substoichiometric colchicine poisoning

1977 • 285 citations

Complete amino acid sequence of alpha-tubulin from porcine brain.

1981 • 272 citations

Aggregation of microtubule subunit protein. Effects of divalent cations, colchicine, and vinblastine

1970 • 237 citations

Effect of Light Scattering on Ultraviolet Difference Spectra¹

1960 • 236 citations

Podophyllotoxin as a probe for the colchicine binding site of tubulin.

1977 • 231 citations

The Chemical Characterization of Calf Brain Microtubule Protein Subunits

1973 • 225 citations

Kinetics and mechanism of colchicine binding to tubulin: evidence for ligand-induced conformational changes

1978 • 221 citations

Promotion of Fluorescence upon Binding of Colchicine to Tubulin

1974 • 218 citations

The Biochemical Events of Mitosis. I. Synthesis and Properties of Colchicine Labeled with Tritium in Its Acetyl Moiety^*

1966 • 207 citations

In Vitro Assembly of Cytoplasmic Microtubules

1980 • 189 citations

Elementary Steps in Enzyme Reactions (as Studied by Relaxation Spectrometry)

1963 • 180 citations

Kinetic analysis of cooperativity in tubulin polymerization in the presence of guanosine di- or triphosphate nucleotides

1978 • 177 citations

The effects of cytochalasins on actin polymerization and actin ATPase provide insights into the mechanism of polymerization.

1980 • 175 citations

Magnesium-induced self-association of calf brain tubulin. I. Stoichiometry

1975 • 175 citations

Reversible dissociation of the αβ dimer of tubulin from bovine brain

1978 • 162 citations

Colchicine inhibition of microtubule assembly via copolymer formation.

1979 • 147 citations

Interaction of tubulin with single ring analogs of colchicine

1982 • 143 citations

Effect of antimitotic drugs on tubulin GTPase activity and self-assembly.

1979 • 142 citations

Interaction of calf brain tubulin with glycerol

1981 • 129 citations

A fluorescence stopped flow study of colchicine binding to tubulin.

1981 • 119 citations

The stabilization of calf-brain microtubule protein by sucrose

1972 • 114 citations

Refractive Indices of Amino Acids, Proteins, and Related Substances

1964 • 108 citations

Circular dichroism study of microtubule protein

1972 • 99 citations

The calculation of partial specific volumes of proteins in guanidine hydrochloride

1974 • 97 citations

Interaction of griseofulvin with microtubules, microtubule protein and tubulin

1977 • 93 citations

Mechanism of colchicine-dimer addition to microtubule ends: implications for the microtubule polymerization mechanism

1980 • 92 citations

Changes in the circular dichroic spectrum of colchicine associated with its binding to tubulin

1981 • 91 citations

Physical-chemical study of daunomycin-tubulin interactions

1977 • 59 citations

Conformational study of calf brain tubulin

1978 • 58 citations

A Quantitative Analysis of Tubulin-Colchicine Binding to Microtubules

1980 • 55 citations

Die Umwandlung des Colchicins durch Sonnenlicht

1951 • 53 citations

STRUCTURAL STABILITY OF CALF BRAIN MICROTUBULE PROTEIN*

1975 • 50 citations

[10] Light scattering and differential refractometry

1973 • 44 citations

The ligand- and microtubule assembly-induced GTPase activity of purified calf brain tubulin

1981 • 43 citations

Aging of tubulin at neutral pH

1982 • 39 citations

Fluorometric assay of tubulin-colchicine complex

1975 • 31 citations

8 Some Physical Probes of Enzyme Structure in Solution

1970 • 29 citations

A thermodynamic study of colchicine and colcemid dimerization.

1981 • 20 citations

cAMP inhibits the in vitro assembly of microtubules

1979 • 17 citations

The interactions of tropolone with magnesium ions and tubulin

1982 • 13 citations