Oligomerization of the α1a- and α1b-Adrenergic Receptor Subtypes

G-protein-coupled receptor heterodimerization modulates receptor function

1999 • 1,146 citations

The GxxxG motif: A framework for transmembrane helix-helix association

2000 • 905 citations

Receptors for Dopamine and Somatostatin: Formation of Hetero-Oligomers with Enhanced Functional Activity

2000 • 866 citations

A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation

1996 • 758 citations

A Trafficking Checkpoint Controls GABAB Receptor Heterodimerization

2000 • 666 citations

Detection of β ₂ -adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

2000 • 631 citations

Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes

2003 • 591 citations

Dimerization: An Emerging Concept for G Protein–Coupled Receptor Ontogeny and Function

2002 • 580 citations

Subtypes of the Somatostatin Receptor Assemble as Functional Homo- and Heterodimers

2000 • 528 citations

The chemokine SDF‐lα triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway

1999 • 510 citations

Increased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness

2001 • 485 citations

Using GFP in FRET-based applications

1999 • 482 citations

Dimerization of the δ Opioid Receptor:

1997 • 479 citations

Quantitative Assessment of β1- and β2-Adrenergic Receptor Homo- and Heterodimerization by Bioluminescence Resonance Energy Transfer

2002 • 466 citations

Functionally Different Agonists Induce Distinct Conformations in the G Protein Coupling Domain of the β2Adrenergic Receptor

2001 • 361 citations

G protein-coupled-receptor cross-talk: the fine-tuning of multiple receptor-signalling pathways

1998 • 318 citations

G-protein-coupled receptors function as oligomers in vivo

2000 • 313 citations

Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during Biosynthesis

2003 • 303 citations

The Fourth Transmembrane Segment Forms the Interface of the Dopamine D2 Receptor Homodimer

2003 • 285 citations

Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking

2001 • 278 citations

Heterodimerization of Somatostatin and Opioid Receptors Cross-modulates Phosphorylation, Internalization, and Desensitization

2002 • 259 citations

Monitoring Receptor Oligomerization Using Time-resolved Fluorescence Resonance Energy Transfer and Bioluminescence Resonance Energy Transfer

2001 • 257 citations

Identification and Molecular Characterization of m3 Muscarinic Receptor Dimers

1999 • 250 citations

Heteromeric association creates a P2Y-like adenosine receptor

2001 • 228 citations

β1/β2-Adrenergic Receptor Heterodimerization Regulates β2-Adrenergic Receptor Internalization and ERK Signaling Efficacy

2002 • 210 citations

G protein-coupled receptor signalling and cross-talk

2002 • 194 citations

Constitutive and Agonist-dependent Homo-oligomerization of the Thyrotropin-releasing Hormone Receptor

2001 • 194 citations

Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells

2002 • 186 citations

Identification of the Cysteine Residues in the Amino-terminal Extracellular Domain of the Human Ca2+ Receptor Critical for Dimerization

1999 • 184 citations

Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues.

1995 • 183 citations

Metabotropic Glutamate 1α and Adenosine A1 Receptors Assemble into Functionally Interacting Complexes

2001 • 179 citations

G protein coupled receptor dimerization: implications in modulating receptor function

2001 • 173 citations

Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.

1992 • 157 citations

Heterodimerization of Calcium Sensing Receptors with Metabotropic Glutamate Receptors in Neurons

2001 • 155 citations

Dimerization and Domain Swapping in G-Protein-Coupled Receptors A Computational Study

2000 • 137 citations

Gonadotropin-releasing Hormone Receptor Microaggregation

2001 • 136 citations

Agonist-dependent Dissociation of Oligomeric Complexes of G Protein-coupled Cholecystokinin Receptors Demonstrated in Living Cells Using Bioluminescence Resonance Energy Transfer

2001 • 125 citations

Characterization of the Phosphorylation Sites Involved in G Protein-coupled Receptor Kinase- and Protein Kinase C-mediated Desensitization of the α1B-Adrenergic Receptor

1997 • 123 citations

The Extracellular N-terminal Domain and Transmembrane Domains 1 and 2 Mediate Oligomerization of a Yeast G Protein-coupled Receptor

2002 • 121 citations

Involvement of the Amino Terminus of the B2 Receptor in Agonist-induced Receptor Dimerization

1999 • 119 citations

Dimerization of the Calcium-sensing Receptor Occurs within the Extracellular Domain and Is Eliminated by Cys → Ser Mutations at Cys101 and Cys236

1999 • 115 citations

Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation.

2000 • 112 citations

The Use of Stimulus-Biased Assay Systems to Detect Agonist-Specific Receptor Active States: Implications for the Trafficking of Receptor Stimulus by Agonists

2000 • 102 citations

G protein-linked receptors: pharmacological evidence for the formation of heterodimers.

1999 • 91 citations

Functional rescue of a constitutively desensitized β2AR through receptor dimerization

1998 • 90 citations

Structural models for dimerization of G‐protein coupled receptors: The opioid receptor homodimers

2002 • 80 citations

Constitutively ActiveAlpha-1b Adrenergic Receptor Mutants Display Different Phosphorylation and Internalization Features

1999 • 73 citations

Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells

2001 • 66 citations

Co- and Posttranslational Modification of the α_1B-Adrenergic Receptor: Effects on Receptor Expression and Function

2002 • 16 citations