Ultrastructure of cell mediated cytotoxicity

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

A differentiation antigen of human NK and K cells identified by a monoclonal antibody (HNK-1).

1981 • 1,411 citations

The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes.

1986 • 1,106 citations

Characteristics of human large granular lymphocytes and relationship to natural killer and K cells

1981 • 1,008 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Isolation of human NK cells by density gradient centrifugation

1980 • 462 citations

Structure, Organization and Polymorphism of Murine and Human T‐Cell Receptor a and β Chain Gene Families

1988 • 448 citations

The IL-2 Receptor β Chain (p70): Role in Mediating Signals for LAK, NK, and Proliferative Activities

1987 • 444 citations

Functional consequences of interleukin 2 receptor expression on resting human lymphocytes. Identification of a novel natural killer cell subset with high affinity receptors.

1990 • 436 citations

Determination of surface antigens on highly purified human NK cells by flow cytometry with monoclonal antibodies.

1981 • 397 citations

Structure and function of human perforin

1988 • 346 citations

Fractionation, morphological and functional characterization of effector cells responsible for human natural killer activity against cell-line targets

1979 • 267 citations

Leu-11+ lymphocytes with natural killer (NK) activity are precursors of recombinant interleukin 2 (rIL 2)-induced activated killer (AK) cells.

1985 • 263 citations

Granzymes, a Family of Serine Proteases Released from Granules of Cytolytic T Lymphocytes upon T Cell Receptor Stimulation

1988 • 263 citations

Internal Disintegration Model of Cytotoxic Lymphocyte-Induced Target Damage

1983 • 225 citations

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies.

1989 • 219 citations

Characteristics and uses of natural killer cells

1988 • 207 citations

Morphologic and phenotypic features of the subpopulation of Leu-2+ cells that suppresses B cell differentiation.

1984 • 196 citations

Recombinant interleukin 2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu 7 and Leu 11 antigens.

1985 • 184 citations

Characterization of the cytolytic reaction mechanism of the human natural killer (NK) lymphocyte: resolution into binding, programming, and killer cell-independent steps.

1982 • 177 citations

Interleukin 2-activated human killer cells are derived from phenotypically heterogeneous precursors.

1986 • 166 citations

Large granular lymphocytes in human peripheral blood: ultrastructural and cytochemical characterization of the granules

1982 • 136 citations

Killing of target cells by lymphocytes: a mechanistic view.

1989 • 134 citations

Ultrastructure of human natural killer cells: nature of the cytolytic contacts in relation to cellular secretion.

1982 • 132 citations

Molecular mechanisms in tumor-cell killing by activated macrophages

1983 • 127 citations

Human lymphokine-activated killer (LAK) cells: identification of two types of effector cells.

1987 • 119 citations

Lymphokine activated killer cells

1989 • 113 citations

Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells.

1990 • 106 citations

Polarization of NK cell cytoskeleton upon conjugation with sensitive target cells.

1983 • 97 citations

Lysis of human solid tumor cells by lymphokine-activated natural killer cells.

1986 • 95 citations

Perforin‐Dependent and ‐Independent Pathways of Cytotoxicity Mediated by Lymphocytes

1988 • 86 citations

The fine structure of normal lymphocyte subpopulations--a study with monoclonal antibodies and the immunogold technique.

1982 • 76 citations

Ultrastructural localization of nonspecific esterase activity in guinea pig and human monocytes, macrophages, and lymphocytes

1981 • 71 citations

Delineation of an effector population responsible for natural killing and antibody-dependent cellular cytotoxicity in man

1981 • 65 citations

Separation and functional studies of the human lymphokine-activated killer cell.

1987 • 65 citations

The role of cell surface recognition structures in the initiation of MHC-unrestricted ‘promiscuous’ killing by T cells

1989 • 57 citations

A New Type of Inclusion Bodies in Lymphocytes

1968 • 55 citations

Ultrastructural analysis of human natural killer cell activation

1987 • 55 citations

A large subpopulation of lymphocytes with T helper phenotype (Leu-3/T4+) exhibits the property of binding to NK cell targets and granular lymphocyte morphology.

1985 • 52 citations

Cytolytic T-cell melodrama

1987 • 51 citations

Morphologic and functional characterization of human peripheral blood T cells expressing the T cell receptor γ/δ*

1989 • 48 citations

Evaluation of surface markers on normal human lymphocytes containing parallel tubular arrays: a quantitative ultrastructural study

1981 • 44 citations

Ultrastructural localization of alpha-naphthyl acid esterase in human TM lymphocytes.

1981 • 44 citations

Surface markers of human natural killer cells as analyzed in a modified single cell cytotoxicity assay on poly-l-lysine coated cover slips

1983 • 43 citations

Synergistic action of a plant rhamnogalacturonan enhancing antitumor cytotoxicity of human natural killer and lymphokine-activated killer cells: chemical specificity of target cell recognition.

1990 • 41 citations

Interaction of lymphokine-activated killer cells with susceptible targets does not induce second messenger generation and cytolytic granule exocytosis.

1989 • 40 citations

Ultrastructural characteristics of human T cell clones with various cytolytic activities

1983 • 38 citations

Large granular lymphocytes: Morphological studies

1982 • 37 citations

The morphology and cytochemistry of human T-cell subpopulations defined by monoclonal antibodies and Fc receptors

1982 • 35 citations

Neue Organelle im peripheren Lymphozyten?^*

1968 • 32 citations

Large-scale preparation of adherent lymphokine-activated killer (A-LAK) cells for adoptive immunotherapy in man

1989 • 30 citations

Identification of a human natural killer cell target cell antigen with monoclonal antibodies.

1989 • 29 citations

Surface Characteristics, Morphology, and Ultrastructure of Human Adherent Lymphokine-Activated Killer Cells

1990 • 28 citations

Parallel tubular arrays in severe combined immunodeficiency disease: an ultrastructural study of peripheral blood lymphocytes

1977 • 27 citations

Ultrastructural characterization of human large granular lymphocyte subsets defined by the expression of HNK-1 (Leu-7), Leu-11, or both HNK-1 and Leu-11 antigens.

1985 • 27 citations

In vitro propagation of cultured human natural killer cells expressing the HNK‐1 differentiation antigen and spontaneous cytotoxic function

1983 • 26 citations

Cytotoxic effector cells of the immune system

1989 • 25 citations

A PREVIOUSLY UNDESCRIBED GRANULE WITHIN THE LYMPHOCYTE

1936 • 24 citations

Differential expression of the interleukin 2 receptor β (p75) chain on human peripheral blood natural killer subsets

1990 • 23 citations

Morphology of Interleukin-2-Stimulated Human Peripheral Blood Mononuclear Effector Cells Killing Glioma-Derived Tumor Cells In Vitro

1988 • 22 citations

Granule-Mediated Cytolysis of Target Cells

1988 • 20 citations

New ultrastructural observations: Parallel tubular arrays in human Tγ lymphoid cells

1983 • 19 citations

Parallel tubular arrays in severe combined immunodeficiency disease: an ultrastructural study of peripheral blood lymphocytes

1977 • 18 citations

Selective lysis of target cells by interleukin-2-expanded peripheral blood mononuclear leukocyte clones

1989 • 17 citations

Lymphocytes with parallel tubular structures: Morphologically a distinctive subpopulation

1983 • 16 citations

Natural killer cells expressing the Leu-11 antigen display phagocytic activity for 2-aminoethylisothiouronium bromide hydrobromide- treated sheep red blood cells.

1986 • 16 citations

Morphologic analysis of human lymphokine‐activated killer (LAK) cells

1990 • 15 citations

Current Understanding of the Lymphokine-Activated Killer Cell Phenomenon

2015 • 12 citations

Immunoelectron microscopic identification of human NK cells by FITC-conjugated anti-Leu-11a and biotinylated anti-leu-7 antibodies

1985 • 12 citations

Cytotoxic Effector Mechanisms

1989 • 11 citations

Generation of lymphokine-activated killer cell activity from non-NK precursor cells

1988 • 11 citations

Morphology of human T lymphocyte clones.

1983 • 9 citations

Morphological heterogeneity of Leu7, Leu11 and OKM1 positive lymphocyte subsets: an ultrastructural study with the immunogold method.

1987 • 8 citations

A morphological study of membrane lesions during natural killer-mediated lysis.

1990 • 7 citations

Distinct Patterns of Virus‐Specific T Cell‐Mediated Cytolysis of Transformed versus Primary Target Cells

1988 • 6 citations

Deleted Work

1955 • 0 citations