Role of tumor necrosis factor‐α and platelet‐activating factor in neoangiogenesis induced by synovial fluids of patients with rheumatoid arthritis

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

Angiogenic Factors

1987 • 3,702 citations

Interleukin-8 as a Macrophage-Derived Mediator of Angiogenesis

1992 • 2,130 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

INHIBITORY EFFECT OF TNF$alpha; ANTIBODIES ON SYNOVIAL CELL INTERLEUKIN-1 PRODUCTION IN RHEUMATOID ARTHRITIS

1989 • 1,137 citations

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

1993 • 1,031 citations

Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis

1990 • 963 citations

Inhibition of the production and effects of interleukins‐1 and tumor necrosis factor α in rheumatoid arthritis

1995 • 917 citations

A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor.

1992 • 807 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Quantitative analysis of cytokine gene expression in rheumatoid arthritis.

1990 • 610 citations

Localization of Tumor Necrosis Factor α in Synovial Tissues and at the Cartilage–Pannus Junction in Patients With Rheumatoid Arthritis

1991 • 585 citations

Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum

1988 • 570 citations

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis.

1994 • 570 citations

Peptide Regulatory Factors

1989 • 498 citations

Tumor necrosis factor/cachectin stimulates peritoneal macrophages, polymorphonuclear neutrophils, and vascular endothelial cells to synthesize and release platelet-activating factor.

1987 • 364 citations

Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.

1988 • 335 citations

Tumour necrosis factor in synovial exudates.

1988 • 242 citations

Synovial fluid concentration of five different cytokines in rheumatic diseases.

1990 • 226 citations

Analysis of the histologic variation of synovitis in rheumatoid arthritis

1988 • 217 citations

Localization of tumor necrosis factor receptors in the synovial tissue and cartilage‐pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor α

1992 • 216 citations

Angiogenesis and rheumatoid arthritis: pathogenic and therapeutic implications.

1992 • 212 citations

Cytokines in synovial fluid: II. The presence of tumour necrosis factor and interferon.

1988 • 191 citations

Role of the SIKVAV Site of Laminin in Promotion of Angiogenesis and Tumor Growth: An In Vivo Matrigel Model

1992 • 185 citations

Production of platelet-activating factor by chick retina.

1986 • 157 citations

Distribution, activation and tryptase/chymase phenotype of mast cells in the rheumatoid lesion.

1995 • 156 citations

Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells.

1987 • 152 citations

Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis.

1994 • 149 citations

Stimulation of neovascularization by human rheumatoid synovial tissue macrophages

1986 • 137 citations

Platelet-activating factor (PAF) enhances tumor necrosis factor production by alveolar macrophages. Prevention by PAF receptor antagonists and lipoxygenase inhibitors.

1989 • 117 citations

Characteristics of tumor necrosis factor production in rheumatoid arthritis

1989 • 115 citations

Pharmacologic activity of bepafant (WEB 2170), a new and selective hetrazepinoic antagonist of platelet activating factor.

1990 • 114 citations

Platelet-activating factor directly stimulates in vitro migration of endothelial cells and promotes in vivo angiogenesis by a heparin-dependent mechanism.

1995 • 108 citations

Platelet activating factor produced in vitro by Kaposi's sarcoma cells induces and sustains in vivo angiogenesis.

1995 • 102 citations

Enhanced expression of tumor necrosis factor receptor mRNA and protein in mononuclear cells isolated from rheumatoid arthritis synovial joints

1992 • 93 citations

PAF molecular heterogeneity: pathobiological implications.

1993 • 78 citations

Role of α1-proteinase inhibitor in restraining peritoneal inflammation in CAPD patients

1992 • 29 citations